| Type | Description |
|---|---|
| Definition | early B cell factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:30:00 | C/EBPalpha induces Ebf1 gene expression in common lymphoid progenitors. | 33332417 |
| 2020-05-30 13:00:00 | The results suggest that EBF1 regulates metanephric development at the last stages of glomerular maturation through its actions in the stromal progenitor (Foxd1+) lineage where it mediates proper regulation of calcineurin/NFAT signaling and COX-2 expression. | 31405952 |
| 2020-04-25 10:16:00 | Conditional deletion of Ebf1 in mesenchymal stem cells altered their cellular composition, chromatin structure and gene expression profiles, including the reduced expression of adhesion-related genes. Functionally, the stromal-specific Ebf1 inactivation results in impaired adhesion of hematopoietic stem cells, leading to reduced quiescence and diminished myeloid output. | 32066955 |
| 2018-09-22 10:39:00 | EBF1 heterozygosity resulted in the deregulation of at least eight transcription factors involved in lymphopoiesis and the deregulation of key proteins playing crucial roles in survival, development, and differentiation of pro-B lymphocytes. | 29181981 |
| 2018-07-07 11:33:00 | Down-regulation of EBF1 (and EBF2) genes leads to a severe impairment of myelin formation in Schwann cells. | 27889898 |
| Type | IDs |
|---|---|
| Synonymous | Ebf, O/E-1, OE-1, Olf-1, Olf1 |
| Gene |
UniProtKB-ID:
COE1_MOUSE,
Q3UTW6_MOUSE,
Q5SWK5_MOUSE,
Q5SWK4_MOUSE,
Q8CBL7_MOUSE
UniprotKB:
Q07802,
Q3UTW6,
Q5SWK5,
Q5SWK4,
Q8CBL7
UniParc:
UPI00005ABE9F,
UPI000000D95E,
UPI00004704A2,
UPI000002A6FA,
UPI00000E94AC
EMBL:
L12147,
BC139362,
AL603913,
AK141175,
AL645607,
AK035781,
BC139364,
AK139021,
AL732622,
AL672013
Ensembl:
ENSMUSG00000057098
KO:
mmu:13591
|
| Nucleutide sequences |
EMBL-CDS:
AAA37533.1,
BAE23864.1,
AAI39365.1,
AAI39363.1,
BAE24573.1,
BAC29185.1
Ensembl_TRS:
ENSMUST00000081265,
ENSMUST00000101326
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000080020,
ENSMUSP00000099857
RefSeq:
NP_001349507.1,
NP_001349500.1,
NP_001349498.1,
NP_001277638.1,
NP_001349508.1,
NP_031923.1,
XP_017169739.1,
NP_001349506.1,
NP_001277639.1,
NP_001349505.1,
XP_030101380.1,
NP_001349503.1,
NP_001277640.1,
NP_001349504.1,
XP_036012180.1
|
| Others |
UniRef100:
UniRef100_E5RFQ1,
UniRef100_Q5SWK4,
UniRef100_Q9UH73
UniRef90:
UniRef90_E5RFQ1,
UniRef90_Q07802-2
UniRef50:
UniRef50_Q07802-2,
UniRef50_A0A3B5B0Z9
UniGene:
Mm.439662,
Mm.440346
CCDS:
CCDS24566.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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