| Type | Description |
|---|---|
| Definition | E4F transcription factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-01-27 10:10:00 | these data identify E4F1 as a master regulator of the PDC. | 27621446 |
| 2018-01-27 10:10:00 | These data reveal a central role for Dlat in the metabolic program regulated by E4F1 in basal keratinocytes. | 27621431 |
| 2016-01-16 12:03:00 | Acute inactivation of E4F1 in these cells results in CHK1-dependent checkpoint deficiency and multiple mitochondrial dysfunctions that lead to increased production, energy stress, and inhibition of de novo pyrimidine synthesis | 25843721 |
| 2016-01-16 10:47:00 | Altogether, our results classify E4F1 as a master regulator of CHK1 activity that ensures high fidelity of DNA replication, thus safeguarding genome stability. | 25843717 |
| 2011-09-10 11:00:00 | deletion of E4F1 resulted in the death of histiocytic sarcoma cells and tumor regression in vivo and extended the lifespan | 21708927 |
| Type | IDs |
|---|---|
| Synonymous | p120E4F, phi-AP3 |
| Gene |
UniProtKB-ID:
E4F1_MOUSE
UniprotKB:
Q8CCE9
UniParc:
UPI00000E93A3,
UPI0001662FEC,
UPI0001662FE7,
UPI0001662FEB,
UPI0001662FED
EMBL:
BC046459,
AK144176,
X76858,
AF126967,
AK033285,
BC057011,
BC071228
Ensembl:
ENSMUSG00000024137
KO:
mmu:13560
|
| Nucleutide sequences |
EMBL-CDS:
BAE25748.1,
AAF22563.1,
AAH71228.1,
CAA54188.1,
AAH57011.1,
AAH46459.1,
BAC28222.1
Ensembl_TRS:
ENSMUST00000056032,
ENSMUST00000226941
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000154444,
ENSMUSP00000062344
RefSeq:
XP_036016189.1,
XP_036016187.1,
NP_001288713.1,
NP_031919.2,
XP_036016188.1,
NP_001342637.1
|
| Others |
UniRef100:
UniRef100_Q8CCE9
UniRef90:
UniRef90_Q8CCE9
UniRef50:
UniRef50_Q66K89
UniGene:
Mm.163132
CCDS:
CCDS28481.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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