| Type | Description |
|---|---|
| Definition | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:21:00 | microRNAs expression correlates with levels of APP, DYRK1A, hyperphosphorylated Tau and BDNF in the hippocampus of a mouse model for Down syndrome during ageing. | 31605772 |
| 2020-11-21 13:32:00 | A Munc18-1 mutant mimicking phosphorylation by Down Syndrome-related kinase Dyrk1a supports normal synaptic transmission and promotes recovery after intense activity. | 32081899 |
| 2020-10-31 13:14:00 | Downregulated Wnt/beta-catenin signalling in the Down syndrome hippocampus. | 31086297 |
| 2020-07-18 11:18:00 | directly interacted with insulin receptor substrate-2 (IRS2) and promoted IRS2 phosphorylation, leading to the proteasomal degradation of IRS2 and promotion of beta cell dysfunction and apoptosis | 31306739 |
| 2020-06-27 11:26:00 | DYRK1A directly interacted with IRS-1 and phosphorylated IRS-1's multiple serine residues. Of note, DYRK1A and IRS-1 were coordinately up-regulated in the prefrontal cortex of db/db mice brain. | 31723029 |
| Type | IDs |
|---|---|
| Synonymous | 2310043O08Rik, D16Ertd272e, D16Ertd493e, Dyrk, Gm10783, Mnbh, Mp86, mmb |
| Gene |
UniProtKB-ID:
DYR1A_MOUSE,
F6U6X3_MOUSE,
Q8C774_MOUSE,
A9C475_MOUSE,
A1L341_MOUSE
UniprotKB:
Q61214,
F6U6X3,
Q8C774,
A9C475,
A1L341
UniParc:
UPI00001EABD6,
UPI0005AB9567,
UPI00000280D3,
UPI00005AB716
EMBL:
U58497,
BC145405,
CT030190,
BC138716,
AK052390,
BC129889,
BC129888,
AC165271
Ensembl:
ENSMUSG00000022897
KO:
mmu:13548
|
| Nucleutide sequences |
EMBL-CDS:
AAC52994.1,
BAC34971.2,
AAI38717.1,
AAI45406.1,
AAI29889.1,
AAI29890.1
Ensembl_TRS:
ENSMUST00000023614,
ENSMUST00000119878,
ENSMUST00000122284
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000023614,
ENSMUSP00000113660,
ENSMUSP00000112853
RefSeq:
NP_001334660.1,
NP_031916.1,
XP_011244400.1,
XP_011244397.1,
NP_001106860.1,
XP_011244401.1,
XP_011244398.1,
XP_011244396.1,
XP_036015668.1
|
| Others |
UniRef100:
UniRef100_Q8C774,
UniRef100_Q61214,
UniRef100_A1L341
UniRef90:
UniRef90_Q13627,
UniRef90_Q8C774
UniRef50:
UniRef50_Q13627,
UniRef50_A0A2I3MUD0
UniGene:
Mm.310973
CCDS:
CCDS28350.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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