| Type | Description |
|---|---|
| Definition | CD109 molecule |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:35:00 | CD109 mediates tumorigenicity and cancer aggressiveness via regulation of EGFR and signalling in cervical squamous cell carcinoma. | 32507856 |
| 2021-02-27 13:46:00 | CD109 promotes the tumorigenic ability and metastatic motility of pancreatic ductal adenocarcinoma cells. | 32007357 |
| 2020-10-31 13:13:00 | CD109 acts as a gatekeeper of the epithelial trait by suppressing epithelial to mesenchymal transition in squamous cell carcinoma cells in vitro. | 31695056 |
| 2020-10-03 12:59:00 | Glioma-initiating cells at tumor edge gain signals from tumor core cells to promote their malignancy. | 32938908 |
| 2020-06-06 12:34:00 | Expression of CD109 is correlated with the invasive and metastatic capacities of lung adenocarcinoma cells. CD109 is upregulated in tumorous tissues, and CD109 overexpression is associated with tumor progression, distant metastasis, and poor prognosis in patients. Inhibition of CD109 decreases EGFR phosphorylation, diminishes EGF-elicited activation of AKT/mTOR, and sensitizes tumor cells to an EGFR inhibitor. | 32133706 |
| Type | IDs |
|---|---|
| Synonymous | CPAMD7, p180, r150 |
| Gene |
UniProtKB-ID:
CD109_HUMAN
UniprotKB:
Q6YHK3
UniParc:
UPI0000E56EE0,
UPI0000E56EDF,
UPI000006E56B,
UPI000013DE92
EMBL:
EF553520,
AF410459,
AK123960,
AF410460,
BX641095,
AK313636,
AL834478,
AY788891,
AY149920,
AY736557,
AL590428,
AY736555,
AK095888,
AL591480
Ensembl:
ENSG00000156535
KO:
hsa:135228
|
| Nucleutide sequences |
EMBL-CDS:
BAC04642.1,
AAU94642.1,
CAE46045.1,
AAU94644.1,
AAL84159.1,
BAG36395.1,
BAG53987.1,
AAL84160.1,
AAN78483.1,
AAX14639.1,
CAD39137.1,
ABQ66266.1
Ensembl_TRS:
ENST00000437994,
ENST00000422508,
ENST00000287097
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000388062,
ENSP00000287097,
ENSP00000404475
RefSeq:
NP_598000.2,
NP_001153059.1,
NP_001153060.1
|
| Others |
UniRef100:
UniRef100_Q6YHK3
UniRef90:
UniRef90_Q6YHK3
UniRef50:
UniRef50_Q6YHK3
UniGene:
Hs.399891
CCDS:
CCDS4982.1,
CCDS55039.1,
CCDS55038.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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