| Type | Description |
|---|---|
| Definition | desmoglein 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 12:20:00 | Found that the expression of skeletal muscle actin (Acta1) was increased in the myocardium of Dsg2 mutant and Dsg2cKO mice prior to lesion formation, and show that Acta1 expression further increases during disease progression with a conspicuous accumulation of F-actin at intercalated discs | 30659114 |
| 2020-01-04 12:39:00 | Dsg2 expression dramatically enhances the rate of spontaneous basal cell carcinoma (BCC) formation in mouse models of Gorlin syndrome. In vitro studies showed that Dsg2 potentiates canonical hedgehog (Hh) signaling and Stat3 activation in ASZ001 BCC cells in both an autocrine and paracrine manner. Data showed that Dsg2 induces a paracrine mediator that stimulates the canonical Hh signaling through Stat3. | 30291846 |
| 2019-09-14 12:50:00 | This study demonstrates that Dsg2 induces epidermal activation of various signaling cascades and accelerates cutaneous wound healing, in part, through urokinase-type plasminogen activator receptor-related signaling cascades | 29753032 |
| 2019-06-01 12:01:00 | hape and number of desmosomes as well as the expression of Dsg2 and the desmosomal plaque protein desmoplakin (Dsp) were investigated by electron microscopy and immunohistochemistry in 12 oestrous-dated mice. | 29938327 |
| 2019-04-13 12:30:00 | these results demonstrate that Dsg2, but not desmocollin 2 is required for the integrity of the intestinal epithelial barrier in vivo | 30115995 |
| Type | IDs |
|---|---|
| Synonymous | AA408168, D18Ertd293e |
| Gene |
UniProtKB-ID:
DSG2_MOUSE
UniprotKB:
O55111
UniParc:
UPI0000195C3E
EMBL:
BC131653,
BC131654,
AB072269,
AJ000328,
BC034056
Ensembl:
ENSMUSG00000044393
KO:
mmu:13511
|
| Nucleutide sequences |
EMBL-CDS:
AAI31655.1,
BAB86843.1,
AAI31654.1,
AAH34056.1,
CAA03995.1
Ensembl_TRS:
ENSMUST00000059787
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000057096
RefSeq:
NP_031909.2
|
| Others |
UniRef100:
UniRef100_O55111
UniRef90:
UniRef90_O55111
UniRef50:
UniRef50_O55111
UniGene:
Mm.345891
CCDS:
CCDS29084.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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