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134637 ADAT2

134637

ADAT2

adenosine deaminase tRNA specific 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition adenosine deaminase tRNA specific 2

研究结论

Date Results Publications
2021-01-23 13:02:00 Identification and rescue of a tRNA wobble inosine deficiency causing intellectual disability disorder. 32763916
2017-08-19 12:29:00 Transfer RNAs (tRNAs) are among the most heavily modified RNA species. Data confirm that ADAT2 exhibits substrate specificity that includes tRNA(Ala-AGC) and tRNA(Thr-AGU), deaminating adenosine-34 to inosine-34 as post-transcriptional modifications. 28703578
2010-10-04 12:40:00 data indicate that ATAD2 overexpression in somatic cells, by acting on basic properties of chromatin, may contribute to malignant transformation 20581866

名称对应

Type IDs
Synonymous DEADC1, TAD2, dJ20N2, dJ20N2.1
Gene
UniProtKB-ID: ADAT2_HUMAN
UniprotKB: Q7Z6V5
UniParc: UPI00001A3A7E, UPI00001A9DC6
EMBL: BX538182, BC037955, CH471051, AL031320, AK126201
Ensembl: ENSG00000189007
KO: hsa:134637
Nucleutide sequences
EMBL-CDS: CAD98054.1, BAG54295.1, EAW47868.1, AAH37955.2
Ensembl_TRS: ENST00000237283, ENST00000606514
Protein sequencees
Ensembl_PRO: ENSP00000475651, ENSP00000237283
RefSeq: NP_001273188.1, XP_011533741.1, NP_872309.2, XP_024302097.1, XP_016865752.1, XP_011533745.1, XP_016865749.1, XP_011533746.1, XP_016865751.1
Others
UniRef100: UniRef100_Q7Z6V5
UniRef90: UniRef90_Q7Z6V5
UniRef50: UniRef50_Q7Z6V5
UniGene: Hs.709561
CCDS: CCDS69219.1, CCDS43511.1

全选

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研究热度

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