| Type | Description |
|---|---|
| Definition | ubiquitin like domain containing CTD phosphatase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 12:26:00 | Study provides evidence that Rpn1-Ser361 is a prevalent phosphosite that is required for proper assembly and activity of the 26S proteasome and identified multiple kinases, including PIM1/2/3, that can phosphorylate Rpn1-S361 and have demonstrated that UBLCP1 is a physiologically relevant phosphatase of this site. Blocking phosphorylation of Rpn1-S361 leads to slowed proliferation and mitochondrial dysfunction. | 31843888 |
| 2018-03-17 11:48:00 | Data show that UBLCP1 selectively binds to the 26S proteasome non-ATPase regulatory subunit 13 (19S regulatory particle) in regulating proteasome assembly. | 28539385 |
| 2013-12-14 12:05:00 | the high-resolution solution structure of the UBL domain of human UBLCP1 and its interaction with Rpn1 | 23667555 |
| 2012-01-28 12:16:00 | UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity | 21949367 |
| Type | IDs |
|---|---|
| Synonymous | CPUB1 |
| Gene |
UniProtKB-ID:
UBCP1_HUMAN
UniprotKB:
Q8WVY7
UniParc:
UPI0000071EAA
EMBL:
CH471062,
BC013425,
AY444562,
AK057996
Ensembl:
ENSG00000164332
KO:
hsa:134510
|
| Nucleutide sequences |
EMBL-CDS:
BAB71628.1,
EAW61577.1,
EAW61578.1,
AAS68538.1,
AAH13425.2
Ensembl_TRS:
ENST00000296786
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000296786
RefSeq:
NP_659486.2
|
| Others |
UniRef100:
UniRef100_Q8WVY7
UniRef90:
UniRef90_Q8WVY7
UniRef50:
UniRef50_Q8WVY7
UniGene:
Hs.591733
CCDS:
CCDS4345.1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| 1 |
University of Toronto |
6 |
| 2 |
Dana-Farber Cancer Institute |
4 |
| 3 |
University of California |
3 |
| 4 |
McGill University |
2 |
| 5 |
Institute for Research in Biomedicine (IRB Barcelona) |
2 |
| 排名 | 研究人员 | 文献 |
|---|---|---|
| 1 |
David E Hill |
3 |
| 2 |
Amélie Dricot |
3 |
| 3 |
Marc Vidal |
3 |
| 4 |
Frederick P Roth |
3 |
| 5 |
Tong Hao |
3 |