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13449 Dok2

13449

Dok2

docking protein 2

protein-coding

Mus musculus

基因描述

Type Description
Definition docking protein 2

研究结论

Date Results Publications
2019-11-09 10:23:00 compound-heterozygous deletion of Dok2 and Dusp4 in mice resulted in lung tumorigenesis with short latency and high incidence, and that their co-deletion synergistically activated MAPK signaling and promoted cell proliferation. 30475228
2018-04-14 11:55:00 findings demonstrate that Dok-3 and Dok-1/-2 play distinctive but cooperative roles in osteoclastogenesis and protect mice from osteopenia, providing physiological and pathophysiological insight into bone homeostasis. 29548825
2017-08-19 11:14:00 These results reveal the critical involvement of Dok-1 and Dok-2 in a negative-feedback loop that prevents overactivation of CD8(+) T cells and promotes memory formation. 27664281
2017-07-29 12:50:00 Thus, Dok-1 and Dok-2 promote survival of glycoprotein B-specific CD8(+) T cells in trigeminal ganglia latently infected with herpes simplex virus 1. 28490594
2017-07-29 11:40:00 this study shows that Dok1 and Dok2 proteins are involved in the control of hematopoietic stem cell cycle regulation 27183638

名称对应

Type IDs
Synonymous DokR, Frip, dok-R
Gene
UniProtKB-ID: DOK2_MOUSE, Q3TX09_MOUSE
UniprotKB: O70469, Q3TX09
UniParc: UPI0000021DF3
EMBL: AK159466, AF030627, AK158246, AF035117, BC004590, AF059583, AK159472
Ensembl: ENSMUSG00000022102
KO: mmu:13449
Nucleutide sequences
EMBL-CDS: AAC31315.1, AAH04590.1, AAC78606.1, AAC13266.1, BAE34423.1, BAE35107.1, BAE35113.1
Ensembl_TRS: ENSMUST00000022698
Protein sequencees
Ensembl_PRO: ENSMUSP00000022698
RefSeq: XP_011243245.1, XP_036014327.1, XP_036014328.1, XP_036014329.1, XP_036014330.1, NP_034201.1, XP_017171323.1
Others
UniRef100: UniRef100_O70469
UniRef90: UniRef90_O70469
UniRef50: UniRef50_O70469
UniGene: Mm.243323
CCDS: CCDS27262.1

全选

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