| Type | Description |
|---|---|
| Definition | docking protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-04-14 11:55:00 | findings demonstrate that Dok-3 and Dok-1/-2 play distinctive but cooperative roles in osteoclastogenesis and protect mice from osteopenia, providing physiological and pathophysiological insight into bone homeostasis. | 29548825 |
| 2018-01-06 10:37:00 | Platelets from Dok-1-/- mice displayed normal aggregation, activation of integrin alphaIIbbeta3, P-selectin surface expression, and soluble fibrinogen binding. These findings indicate that Dok-1 does not affect "inside-out" platelet signalling. | 26790499 |
| 2017-11-25 13:17:00 | in the absence of PAG, Csk becomes more associated with alternative partners; i.e., phosphatase PTPN22 and Dok adaptors. Combining PAG deficiency with PTPN22 or Dok adaptor deficiency further enhances effector T cell responses. Unlike PAG, Cbl ubiquitin ligases inhibit the activation of naive, but not of effector, T cells. | 27926878 |
| 2017-08-19 11:14:00 | These results reveal the critical involvement of Dok-1 and Dok-2 in a negative-feedback loop that prevents overactivation of CD8(+) T cells and promotes memory formation. | 27664281 |
| 2017-07-29 12:50:00 | Thus, Dok-1 and Dok-2 promote survival of glycoprotein B-specific CD8(+) T cells in trigeminal ganglia latently infected with herpes simplex virus 1. | 28490594 |
| Type | IDs |
|---|---|
| Synonymous | AW557123, p62DOK |
| Gene |
UniProtKB-ID:
DOK1_MOUSE,
Q3UWF9_MOUSE
UniprotKB:
P97465,
Q3UWF9
UniParc:
UPI0000020ACB,
UPI00005ABCA0
EMBL:
AK136382,
AF084363,
U78818,
BC013066
Ensembl:
ENSMUSG00000068335
KO:
mmu:13448
|
| Nucleutide sequences |
EMBL-CDS:
AAB48827.2,
AAC95339.1,
AAH13066.1,
BAE22956.1
Ensembl_TRS:
ENSMUST00000089651
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000087079
RefSeq:
XP_030111000.1,
NP_034200.4,
NP_001278728.1,
XP_036021698.1
|
| Others |
UniRef100:
UniRef100_Q3UWF9,
UniRef100_P97465
UniRef90:
UniRef90_P97465
UniRef50:
UniRef50_P97465
UniGene:
Mm.156
CCDS:
CCDS20265.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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