| Type | Description |
|---|---|
| Definition | double C2, alpha |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:12:00 | Doc2b Ca(2+) binding site mutants enhance synaptic release at rest at the expense of sustained synaptic strength. | 31594980 |
| 2020-09-05 13:57:00 | Doc2 Proteins Are Not Required for the Increased Spontaneous Release Rate in Synaptotagmin-1-Deficient Neurons. | 32098902 |
| 2019-08-10 11:02:00 | Doc2alpha promoted glutamatergic spontaneous neurotransmitter release, while Doc2beta and syt1 both regulated GABAergic spontaneous neurotransmitter release. | 29754754 |
| 2015-07-25 11:14:00 | study identifies a critical role for DOC2B in insulin-stimulated glucose uptake in adipocytes, and for the synergistic regulation of GSIS by DOC2A and DOC2B in beta cells. | 25005332 |
| 2010-07-26 11:50:00 | The polybasic sequence in the C2B domain functions as a binding site for syntaxin-1a/SNAP-25 heterodimer and controls the number of 'readily releasable' vesicles in neuroendocrine cells. | 20403080 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
DOC2A_MOUSE
UniprotKB:
Q7TNF0
UniParc:
UPI00001B9476
EMBL:
BC055768
Ensembl:
ENSMUSG00000052301
KO:
mmu:13446
|
| Nucleutide sequences |
EMBL-CDS:
AAH55768.1
Ensembl_TRS:
ENSMUST00000064110
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000070119
RefSeq:
NP_001355287.1,
NP_034199.1,
XP_036008535.1,
NP_001355284.1,
XP_036008534.1,
XP_036008533.1,
NP_001355286.1,
NP_001355285.1
|
| Others |
UniRef100:
UniRef100_Q7TNF0
UniRef90:
UniRef90_Q7TNF0
UniRef50:
UniRef50_Q7TNF0
UniGene:
Mm.266301
CCDS:
CCDS21847.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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