| Type | Description |
|---|---|
| Definition | POC5 centriolar protein |
| Date | Results | Publications |
|---|---|---|
| 2019-12-07 11:21:00 | POC5 mutation is associated with impairment of cell cycle, cilia length and centrosome protein interactions in Adolescent idiopathic scoliosis. | 30845169 |
| 2019-01-12 10:08:00 | The findings demonstrate that Poc5 is important for normal retinal development and function. Altogether, this study presents POC5 as a novel gene involved autosomal recessively inherited RP, and strengthens the hypothesis that mutations in centriolar proteins are important cause of retinal dystrophies. | 29272404 |
| 2018-11-03 10:10:00 | Common variant rs6892146 of POC5 is associated with the development of adolescent idiopathic scoliosis in the Chinese population. | 29189569 |
| 2017-08-12 10:31:00 | Depletion of CEP295 blocks the incorporation of POC5 and POC1B into the distal portion of centrioles and suppresses the post-translational modification of centriolar microtubules . Our study thus uncovers a new role for CEP295 during centriole elongation. | 27185865 |
| 2015-05-16 10:08:00 | Mutations in the POC5 gene contribute to the occurrence of idiopathic scoliosis. | 25642776 |
| Type | IDs |
|---|---|
| Synonymous | C5orf37 |
| Gene |
UniProtKB-ID:
POC5_HUMAN
UniprotKB:
Q8NA72
UniParc:
UPI000020CB20,
UPI00005764F4,
UPI0000F5346F
EMBL:
AK093098,
AK296071,
BC101328,
BC101326,
BC065750,
BC101325,
BC101327
Ensembl:
ENSG00000152359
KO:
hsa:134359
|
| Nucleutide sequences |
EMBL-CDS:
AAI01326.1,
AAI01328.1,
BAG58829.1,
AAH65750.1,
BAC04054.1,
AAI01327.1
Ensembl_TRS:
ENST00000446329,
ENST00000428202,
ENST00000510798
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000426796,
ENSP00000410216,
ENSP00000399481
RefSeq:
XP_016864526.1,
NP_001092741.1,
XP_016864529.1,
NP_689621.2,
XP_024310131.1,
XP_011541462.1,
XP_011541460.1,
XP_005248493.1,
XP_011541461.1,
XP_024310130.1
|
| Others |
UniRef100:
UniRef100_Q8NA72
UniRef90:
UniRef90_Q8NA72
UniRef50:
UniRef50_Q8NA72
UniGene:
Hs.432726
CCDS:
CCDS47237.1,
CCDS47236.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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