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134353 LSM11

134353

LSM11

LSM11, U7 small nuclear RNA associated

protein-coding

Homo sapiens

基因描述

Type Description
Definition LSM11, U7 small nuclear RNA associated

研究结论

Date Results Publications
2021-02-02 13:28:00 cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing. 33230297
2020-03-21 12:05:00 While the molecular basis for this altered cleavage activity is unknown, one possibility is that binding of Lsm10 and Lsm11 to the spliceosomal Sm site affects the overall geometry of the U7-specific Sm ring, resulting in misalignment of the CPSF73 endonuclease with the substrate. 31819999
2013-04-27 12:09:00 FLASH/Lsm11 complex bind a unique combination of polyadenylation factors 23071092
2010-01-21 00:00:00 Lsm10 and Lsm11, which replace the Sm proteins D1 and D2 in the histone RNA processing U7 snRNPs, associate with pICln in vitro and in vivo without receiving sDMA modifications and with PRMT5 and SMN complexes 16087681
2010-01-21 00:00:00 The overexpression of Lsm10 and Lsm11 increases the cellular levels of U7 snRNP but has no effect on histone pre-mRNA processing. 16914750

名称对应

Type IDs
Gene
UniProtKB-ID: LSM11_HUMAN
UniprotKB: P83369
UniParc: UPI0000072830
EMBL: AK095592, BC051353, BC126449
Ensembl: ENSG00000155858
KO: hsa:134353
Nucleutide sequences
EMBL-CDS: BAC04581.1, AAH51353.1, AAI26450.1
Ensembl_TRS: ENST00000286307
Protein sequencees
Ensembl_PRO: ENSP00000286307
RefSeq: NP_775762.1
Others
UniRef100: UniRef100_P83369
UniRef90: UniRef90_P83369
UniRef50: UniRef50_P83369
UniGene: Hs.631954
CCDS: CCDS4342.1

全选

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