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134266 GRPEL2

134266

GRPEL2

GrpE like 2, mitochondrial

protein-coding

Homo sapiens

基因描述

Type Description
Definition GrpE like 2, mitochondrial

研究结论

Date Results Publications
2018-12-22 11:01:00 The dimerization of GRPEL2 may activate the folding machinery responsible for protein import into mitochondrial matrix or enhance the chaperone activity of mitochondrial HSP70, thus protecting mitochondrial proteostasis in oxidative stress. 30098457
2017-11-26 00:32:00 Data suggest that two putative NEF (nucleotide exchange factors) orthologs, GRPEL1 and GRPEL2, modulate function of mitochondrial HSP70 (mtHSP70); both GRPEL1 and GRPEL2 associate with mtHSP70 as hetero-oligomeric subcomplex and regulate mtHSP70 transport. (GRPEL = mitochondrial GrpE-like protein; HSP70 = heat-shock protein 70) 28848044
2010-12-05 22:08:00 Observational study of gene-disease association. (HuGE Navigator) 20877624

名称对应

Type IDs
Synonymous Mt-GrpE#2
Gene
UniProtKB-ID: GRPE2_HUMAN
UniprotKB: Q8TAA5
UniParc: UPI00017A6E01, UPI000004A0F1
EMBL: BC070090, AC131025, BC036678, AK294005, AK074293
Ensembl: ENSG00000164284
KO: hsa:134266
Nucleutide sequences
EMBL-CDS: AAH36678.1, BAB85040.1, BAG57367.1, AAH70090.1
Ensembl_TRS: ENST00000416916, ENST00000329271
Protein sequencees
Ensembl_PRO: ENSP00000329558, ENSP00000397302
RefSeq: NP_689620.2
Others
UniRef100: UniRef100_Q8TAA5
UniRef90: UniRef90_Q8TAA5
UniRef50: UniRef50_O88396
UniGene: Hs.511816
CCDS: CCDS4295.1

全选

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研究热度

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