| Type | Description |
|---|---|
| Definition | actin filament associated protein 1 like 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-08-04 12:05:00 | AFAP1L1 promotes cell proliferation, accelerates cell cycle progression, and prevents cell apoptosis in lung cancer cells. | 29323101 |
| 2016-09-17 11:34:00 | data define a novel pathway that directs Lyn/Src family tyrosine kinase signals to sarcoma cell invadopodia through specific recruitment of Vav2 and Nck2 to phosphorylated AFAP1L1, to control cell migration and invasion | 26212012 |
| 2015-04-04 12:16:00 | AFAP1L1 plays a role in the progression of colorectal cancer by modulating cell shape and motility and by inhibiting anoikis, presumably through interactions with vinculin-including protein complexes. | 24723436 |
| 2013-07-06 11:24:00 | Findings indicate a role for transcription factor Sp3 in sarcomas as a driver for expression of the metastasis-related gene AFAP1L1 (actin filament-associated protein 1-like 1). | 23326307 |
| 2011-11-12 10:26:00 | AFAP1L1 has a role in the progression of spindle cell sarcomas and is a prognostic biomarker. | 21516130 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
AF1L1_HUMAN
UniprotKB:
Q8TED9
UniParc:
UPI00000703AC,
UPI0000E447EC,
UPI000007453D,
UPI00001C1E2F
EMBL:
BC040723,
AK074185,
BC125093,
BC125094,
AK095980,
AK094067
Ensembl:
ENSG00000157510
KO:
hsa:134265
|
| Nucleutide sequences |
EMBL-CDS:
AAH40723.1,
BAC04277.1,
AAI25095.1,
BAC04664.1,
BAB85011.1,
AAI25094.1
Ensembl_TRS:
ENST00000296721,
ENST00000515000
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000296721,
ENSP00000424427
RefSeq:
NP_689619.1,
XP_016864525.1,
NP_001309991.1,
NP_001309992.1,
XP_011535860.1,
NP_001139809.1
|
| Others |
UniRef100:
UniRef100_Q8TED9
UniRef90:
UniRef90_Q8TED9
UniRef50:
UniRef50_Q8TED9
UniGene:
Hs.483793
CCDS:
CCDS54932.1,
CCDS34274.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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