| Type | Description |
|---|---|
| Definition | dynein cytoplasmic 1 heavy chain 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-07-01 11:21:00 | demonstrate that the outward transport of dynein from soma to axon terminal is driven by direct interactions with the anterograde motor kinesin-1. | 27210554 |
| 2017-04-22 12:16:00 | The Swl/Swl mutation of Dync1h1 gene led to embryonic mal-development and lethality, whereas the Swl/+ DRG neurons demonstrated deficient retrograde transport in dynein-driven cargos and excessive apoptosis during mid- to late-developmental stages. | 27080913 |
| 2013-05-25 11:37:00 | These data unveil a previously unrecognized role for the dynein-dynactin motor complex in osteoclast formation and function. | 22887640 |
| 2013-04-13 11:00:00 | The Loa heterozygote phenotype is morphometrically depleted; in addition to dendritic axonal defects, the Loa mutation in a mouse model for mixed motor-sensory loss considers the entire neuraxis and is not a model for sensory loss. | 22684941 |
| 2013-03-09 12:17:00 | Snapin-dynein coupling is one of the primary mechanisms driving BDNF-TrkB retrograde transport, thus providing mechanistic insights into the regulation of neuronal growth and survival. | 22840395 |
| Type | IDs |
|---|---|
| Synonymous | 9930018I23Rik, AI894280, DHC1, DHC1a, DNCL, Dnchc1, Dnec1, Dnecl, Loa, MAP1C, P22, Swl, mKIAA0325 |
| Gene |
UniProtKB-ID:
DYHC1_MOUSE
UniprotKB:
Q9JHU4
UniParc:
UPI00001C6B9A
EMBL:
AY004877,
AC152827
Ensembl:
ENSMUSG00000018707
KO:
mmu:13424
|
| Nucleutide sequences |
EMBL-CDS:
AAF91078.1
Ensembl_TRS:
ENSMUST00000018851
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000018851
RefSeq:
NP_084514.2
|
| Others |
UniRef100:
UniRef100_Q9JHU4
UniRef90:
UniRef90_Q9JHU4
UniRef50:
UniRef50_Q14204
UniGene:
Mm.181430
CCDS:
CCDS36559.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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