| Type | Description |
|---|---|
| Definition | dystrophia myotonica-protein kinase |
| Date | Results | Publications |
|---|---|---|
| 2020-02-01 11:01:00 | These results suggest the existence of p53-p73-DMPK axis which mediates DNA-damage induced actomyosin contraction at the cortex and concomitant cell death. | 31480541 |
| 2019-11-16 11:07:00 | MEF2-induced loss of sarcomeres is mediated by DMPK via a decrease in sarcomeric gene expression by interfering with SRF transcriptional activity, leading to adverse cardiomyocyte remodelling and heart failure. | 29648621 |
| 2019-03-09 12:36:00 | We have developed an inducible, skeletal muscle-specific mouse model of DM1 (CUG960) that expresses 960 CUG repeat-expressing animals (CUG960) in the context of human DMPK exons 11-15. | 29771332 |
| 2017-06-10 12:44:00 | Our results support the feasibility and safety of using antisense oligonucleotides for post-transcriptional silencing of DMPK in muscle and heart. | 27522499 |
| 2016-05-21 12:58:00 | Sense DMPK RNA foci clearly co-localize with MBNL1 and MBNL2 proteins and accumulate in myotonic dystrophy 1 tissues during development. | 26339785 |
| Type | IDs |
|---|---|
| Synonymous | DM, DMK, Dm15, MDPK, MT-PK |
| Gene |
UniProtKB-ID:
DMPK_MOUSE,
E9Q6J9_MOUSE
UniprotKB:
P54265,
E9Q6J9
UniParc:
UPI000002A817,
UPI000002A81C,
UPI000002A81B,
UPI000002A81E,
UPI000002A818,
UPI00015AA486,
UPI000002A81D,
UPI0000029AC2,
UPI000002A81A,
UPI000002A816,
UPI000002A819
EMBL:
AC145199,
Z21503,
Z21506,
Z21504,
S60315,
S60316,
AC170864,
S60313,
Z21505,
S60314,
Z38015
Ensembl:
ENSMUSG00000030409
KO:
mmu:13400
|
| Nucleutide sequences |
EMBL-CDS:
AAC60666.1,
AAC60667.1,
CAA86113.1,
CAA79715.1,
AAC60664.1,
AAC60665.1
Ensembl_TRS:
ENSMUST00000032568,
ENSMUST00000238982,
ENSMUST00000108473,
ENSMUST00000108474
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000032568,
ENSMUSP00000158930,
ENSMUSP00000104113,
ENSMUSP00000104114
RefSeq:
XP_006539584.1,
XP_006539585.1,
NP_001366186.1,
NP_115794.1,
XP_006539582.1,
XP_006539583.1,
XP_006539579.1,
NP_001361580.1,
NP_001177420.1,
XP_006539580.1,
NP_001177419.1
|
| Others |
UniRef100:
UniRef100_P54265,
UniRef100_E9Q6J9
UniRef90:
UniRef90_P54265,
UniRef90_E9Q6J9
UniRef50:
UniRef50_Q09013
UniGene:
Mm.6529
CCDS:
CCDS90170.1,
CCDS52054.1,
CCDS39794.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员