| Type | Description |
|---|---|
| Definition | distal-less homeobox 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 13:56:00 | Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. | 30796806 |
| 2019-12-21 11:58:00 | Dlx1 and Dlx2 promote interneuron GABA synthesis, synaptogenesis, and dendritogenesis. Dlx1&2 coordinate key components of cortical interneurons postnatal development by promoting their excitability, inhibitory output, and survival. | 29028947 |
| 2018-12-22 11:46:00 | Overexpression of Dlx2 enhances early chondrocyte differentiation by increasing accumulation of Col2alpha1, type II collagen and aggrecan, but interferes later stages of chondrocyte differentiation through inhibiting MMP13 expression. | 29787757 |
| 2018-12-22 10:28:00 | Studies revealed that Dlx1/2 and Otp are required for the specification of growth hormone-releasing hormone (GHRH)- and AgRP-neurons, respectively. Dlx1/2 suppress agouti-related protein (AgRP)-neuronal fate by directly binding and repressing the Otp gene, uncovering a novel Dlx1/2-Otp gene regulatory axis critical for the segregation of GHRH- and AgRP-neuronal fates. | 29795232 |
| 2018-07-28 12:19:00 | Mutant Runx2 regulates amelogenesis and osteogenesis through a miR-185-5p-Dlx2 axis. | 29242628 |
| Type | IDs |
|---|---|
| Synonymous | AW121999, Dlx-2, Tes-1 |
| Gene |
UniProtKB-ID:
DLX2_MOUSE,
Q52KJ2_MOUSE
UniprotKB:
P40764,
Q52KJ2
UniParc:
UPI000002213C
EMBL:
U51002,
M83184,
M80540,
AK144652,
BC094317
Ensembl:
ENSMUSG00000023391
KO:
mmu:13392
|
| Nucleutide sequences |
EMBL-CDS:
AAA40412.1,
AAA18487.1,
AAB40901.1,
BAE25991.1,
AAH94317.1
Ensembl_TRS:
ENSMUST00000024159
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000024159
RefSeq:
NP_034184.1
|
| Others |
UniRef100:
UniRef100_P40764
UniRef90:
UniRef90_P40764
UniRef50:
UniRef50_P40764
UniGene:
Mm.3896
CCDS:
CCDS16117.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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