| Type | Description |
|---|---|
| Definition | distal-less homeobox 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-02 13:28:00 | Defining compartmentalized stem cell populations with distinct cell division dynamics in the ocular surface epithelium. | 33199446 |
| 2020-10-24 13:56:00 | Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. | 30796806 |
| 2019-12-21 11:58:00 | Dlx1 and Dlx2 promote interneuron GABA synthesis, synaptogenesis, and dendritogenesis. Dlx1&2 coordinate key components of cortical interneurons postnatal development by promoting their excitability, inhibitory output, and survival. | 29028947 |
| 2018-12-22 10:28:00 | Studies revealed that Dlx1/2 and Otp are required for the specification of growth hormone-releasing hormone (GHRH)- and AgRP-neurons, respectively. Dlx1/2 suppress agouti-related protein (AgRP)-neuronal fate by directly binding and repressing the Otp gene, uncovering a novel Dlx1/2-Otp gene regulatory axis critical for the segregation of GHRH- and AgRP-neuronal fates. | 29795232 |
| 2017-09-30 12:14:00 | GABA is the major inhibitory neurotransmitter in the brain. We show that Dlx1/Dlx2 homeobox genes regulate GABA synthesis during forebrain development through direct activation of glutamic acid decarboxylase enzyme isoforms that convert glutamate to GABA. | 28821666 |
| Type | IDs |
|---|---|
| Synonymous | Dlx, Dlx-1 |
| Gene |
UniProtKB-ID:
DLX1_MOUSE
UniprotKB:
Q64317
UniParc:
UPI000002421A
EMBL:
U51001,
BC079609,
X57552,
U51000
Ensembl:
ENSMUSG00000041911
KO:
mmu:13390
|
| Nucleutide sequences |
EMBL-CDS:
AAH79609.1,
AAB40899.1,
AAB40900.1,
CAB37647.1
Ensembl_TRS:
ENSMUST00000037119
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000042413
RefSeq:
XP_006498735.1,
XP_036013950.1,
XP_036013951.1,
NP_034183.1
|
| Others |
UniRef100:
UniRef100_Q64317
UniRef90:
UniRef90_Q64317
UniRef50:
UniRef50_Q64317
UniGene:
Mm.4543,
Mm.475101
CCDS:
CCDS16116.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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