| Type | Description |
|---|---|
| Definition | discs large MAGUK scaffold protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 10:25:00 | DLG1 joins a growing list of genes encoding ion channel interacting proteins (ChIPs) identified as potential channelopathy-susceptibility genes because of their ability to regulate the trafficking, targeting, and modulation of ion channels that are critical for the generation and propagation of the cardiac electrical impulse. | 32196358 |
| 2020-04-18 11:01:00 | The results reveal an unexpected function of Dlg1 in restraining hyper-antibody responses through the inhibition of FoxO1 and thus antigen-binding-induced proliferation in B cells. | 31169885 |
| 2020-03-21 11:13:00 | The carboxyl-terminal region of KIF13B containing the CAP-Gly domain is important for the LRP1-DLG1-KIF13B complex formation with implications in the regulation of metabolism, cell polarity, and development. | 31487503 |
| 2020-02-29 11:26:00 | this study shows that Dlg1 maintains dendritic cell function by securing voltage-gated K(+) channel integrity | 31028120 |
| 2020-01-25 13:43:00 | In vivo analysis of the Dlg1-deficient intestine revealed improper orientation of mitotic spindles and a decreased rate of cellular migration. Loss of Dlg1 decreased survival in Apc(+/min) mice, validating its role as a tumor suppressor in the intestine. | 30552232 |
| Type | IDs |
|---|---|
| Synonymous | B130052P05Rik, Dlgh1, E-dlg/SAP97, SAP-97, SAP97, mKIAA4187 |
| Gene |
UniProtKB-ID:
DLG1_MOUSE,
Q3UP61_MOUSE,
H7BWY4_MOUSE,
E9Q9H0_MOUSE,
D3Z3B8_MOUSE
UniprotKB:
Q811D0,
Q3UP61,
H7BWY4,
E9Q9H0,
D3Z3B8
UniParc:
UPI00006077D2,
UPI00004C8004,
UPI00006077DA,
UPI00001EA68A,
UPI000000BB6D,
UPI0000192CE1,
UPI00005AC230
EMBL:
BC047142,
AC126055,
BC057118,
AK143780,
AY159380,
U93309,
AC129214
Ensembl:
ENSMUSG00000022770
KO:
mmu:13383
|
| Nucleutide sequences |
EMBL-CDS:
AAH47142.1,
AAH57118.1,
AAN87264.1,
AAC31653.1,
BAE25536.1
Ensembl_TRS:
ENSMUST00000064477,
ENSMUST00000115205,
ENSMUST00000100001,
ENSMUST00000023454,
ENSMUST00000115201,
ENSMUST00000115196
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000064280,
ENSMUSP00000097581,
ENSMUSP00000110859,
ENSMUSP00000023454,
ENSMUSP00000110855,
ENSMUSP00000110850
RefSeq:
NP_001239365.1,
XP_030104819.1,
XP_036015660.1,
NP_001239362.1,
XP_030104820.1,
XP_006521835.1,
XP_017172354.1,
XP_006521836.1,
XP_036015663.1,
XP_006521828.1,
XP_006521827.1,
XP_036015661.1,
XP_017172361.1,
NP_001344211.1,
NP_031888.2,
XP_006521826.1,
XP_006521824.1,
NP_001239363.1,
XP_030104822.1,
XP_006521831.1,
XP_006521830.1,
NP_001239364.1,
XP_006521833.1,
NP_001344210.1,
XP_006521825.1,
XP_006521829.1,
XP_006521834.1,
XP_006521832.1,
XP_036015662.1,
XP_017172356.1,
XP_017172358.1,
XP_030104821.1
|
| Others |
UniRef100:
UniRef100_H7BWY4,
UniRef100_D3Z3B8,
UniRef100_Q811D0,
UniRef100_E9Q9H0,
UniRef100_Q3UP61
UniRef90:
UniRef90_Q811D0,
UniRef90_D3Z3B8,
UniRef90_H7BWY4,
UniRef90_A0A0G2K1M2,
UniRef90_Q3UP61
UniRef50:
UniRef50_Q811D0,
UniRef50_A0A3Q2LA49,
UniRef50_Q62696
UniGene:
Mm.382
CCDS:
CCDS28107.1,
CCDS57025.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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