| Type | Description |
|---|---|
| Definition | DNA fragmentation factor, beta subunit |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 12:11:00 | Cell-free DNA in blood circulation is generated by DNase1L3 and caspase-activated DNase. | 31255286 |
| 2018-01-06 12:48:00 | Dff40 expression is upregulated in atherosclerotic plaque. Dff40 deficiency inhibited high-fat diet-induced atherosclerosis, as evidenced by decreased atherosclerotic plaques, inhibited inflammatory response, and macrophage apoptosis, as well as enhanced stability of plaques. | 28007744 |
| 2013-06-01 12:02:00 | the highest order of chromatin compaction observed in the later steps of caspase-dependent apoptosis relies on DFF40/CAD-mediated DNA damage by generating 3'-OH ends in single-strand rather than double-strand DNA nicks/breaks | 23430749 |
| 2010-04-19 11:28:00 | results show that caspase 3/CAD promotes cell differentiation by directly modifying the DNA/nuclear microenvironment, which enhances the expression of critical regulatory genes | 20160104 |
| 2010-01-21 00:00:00 | A los of caspase-activated DNASE enhances tumorigenesis induced by a chemical carcinogen in a model of skin carcinogenesis in mice. | 19541853 |
| Type | IDs |
|---|---|
| Synonymous | 40kDa, 5730477D02Rik, CAD, CPAN, DFF40, Didff |
| Gene |
UniProtKB-ID:
DFFB_MOUSE,
Q8BP66_MOUSE,
Q7TS81_MOUSE
UniprotKB:
O54788,
Q8BP66,
Q7TS81
UniParc:
UPI0000023092,
UPI00001AA20C,
UPI00000EB0FA
EMBL:
BC053052,
AB009377,
AK077619
Ensembl:
ENSMUSG00000029027
KO:
mmu:13368
|
| Nucleutide sequences |
EMBL-CDS:
BAA24977.1,
BAC36905.1,
AAH53052.1
Ensembl_TRS:
ENSMUST00000030893
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000030893
RefSeq:
XP_006538580.1,
XP_030109043.1,
XP_011248485.1,
XP_011248486.1,
NP_031885.3,
XP_036019539.1
|
| Others |
UniRef100:
UniRef100_Q7TS81,
UniRef100_Q8BP66,
UniRef100_O54788
UniRef90:
UniRef90_Q7TS81,
UniRef90_O54788
UniRef50:
UniRef50_O54788
UniGene:
Mm.388918
CCDS:
CCDS19004.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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