| Type | Description |
|---|---|
| Definition | diaphanous related formin 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 11:34:00 | We identify mDia1 as a novel regulator of mast cell response that coordinates mast cell chemotaxis and secretion through its actin-nucleating activity. | 31279009 |
| 2019-09-21 10:13:00 | Deletion of the cytoplasmic domain binding partner Diaph1 suppresses glomerular inflammation as well as podocyte stress and effacement in mouse model of diabetic nephropathy. | 30132346 |
| 2019-05-04 10:47:00 | The authors report that formins mDia1 and mDia2 dissociate faster under higher ionic strength and when actin concentration is increased. Profilin, known to increase the elongation rate of formin-associated filaments, surprisingly decreases the formin dissociation rate, by bringing formin FH1 domains in transient contact with the barbed end. | 29799413 |
| 2019-05-04 10:18:00 | individual and combined, CRISPR/Cas9-mediated disruption of genes encoding mDia1 and -3 formins in B16-F1 mouse melanoma cells revealed enhanced frequency of cells displaying multiple fronts, again accompanied by defects in cell polarization and migration | 30808751 |
| 2019-04-27 11:56:00 | Loss of mDia1/3 impaired these F-actin architectures, induced ectopic noncontractile espin1-containing F-actin bundles, and disrupted Sertoli cell-germ cell interaction, resulting in impaired spermatogenesis. | 30256801 |
| Type | IDs |
|---|---|
| Synonymous | D18Wsu154e, Dia1, Diap1, Drf1, p140mDia |
| Gene |
UniProtKB-ID:
DIAP1_MOUSE,
F6XC54_MOUSE,
E9PV41_MOUSE
UniprotKB:
O08808,
F6XC54,
E9PV41
UniParc:
UPI0000F22210,
UPI000035EB1A,
UPI0000027B7C
EMBL:
U96963,
AC129315
Ensembl:
ENSMUSG00000024456
KO:
mmu:13367
|
| Nucleutide sequences |
EMBL-CDS:
AAC53280.1
Ensembl_TRS:
ENSMUST00000115634,
ENSMUST00000115631,
ENSMUST00000025337
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000111297,
ENSMUSP00000111294,
ENSMUSP00000025337
RefSeq:
NP_001292909.1,
XP_036016863.1,
NP_031884.1,
NP_001292910.1
|
| Others |
UniRef100:
UniRef100_E9PV41,
UniRef100_O08808
UniRef90:
UniRef90_O08808
UniRef50:
UniRef50_O60610
UniGene:
Mm.195916
CCDS:
CCDS57121.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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