| Type | Description |
|---|---|
| Definition | dihydrofolate reductase |
| Date | Results | Publications |
|---|---|---|
| 2020-01-18 11:39:00 | endothelial Rb positively impacts arterial function by supporting vasoprotective endothelial DHFR/nitric oxide pathway activity, leading to reduced abdominal aortic aneurysm development. | 31214845 |
| 2016-09-17 10:26:00 | The study reports arrested hematopoiesis and vascular relaxation defects in mice with a point mutation, Thr136Ala substitution in Dhfr. | 26830229 |
| 2016-02-06 11:38:00 | S-nitrosylation of DHFR at cysteine 7 by eNOS-derived NO is crucial for DHFR stability. | 26381869 |
| 2015-10-03 10:55:00 | demonstrate that dihydrofolate reductase activity is also a feature of the mitochondria in both rat and mouse but this is not due to a second enzyme | 25980602 |
| 2012-06-02 10:21:00 | Robust and processive unfolding/degradation of some substrates with very stable protein domains, including mDHFR and titin(I27) . | 22162032 |
| Type | IDs |
|---|---|
| Synonymous | 8430436I03Rik, AA607882, AI662710, AW555094 |
| Gene |
UniProtKB-ID:
DYR_MOUSE,
Q544T5_MOUSE
UniprotKB:
P00375,
Q544T5
UniParc:
UPI000000189B
EMBL:
M10722,
J00387,
M10071,
M10811,
L26316,
J00386,
V00731,
AK031241,
J00383,
X56066,
AK136212,
V00733,
V00734,
BC005796,
J00382,
J00385,
J00384
Ensembl:
ENSMUSG00000021707
KO:
mmu:13361
|
| Nucleutide sequences |
EMBL-CDS:
CAB43539.2,
AAA37637.1,
CAA24112.1,
AAH05796.1,
AAA37523.1,
AAA37638.1,
AAA37524.1,
CAA24111.1,
CAA39544.1,
AAA37525.1,
BAC27315.1,
BAE22879.1
Ensembl_TRS:
ENSMUST00000022218
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000022218
RefSeq:
NP_034179.1
|
| Others |
UniRef100:
UniRef100_P00375
UniRef90:
UniRef90_P00375
UniRef50:
UniRef50_P00375
UniGene:
Mm.23695
CCDS:
CCDS26680.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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