Type | Description |
---|---|
Definition | 7-dehydrocholesterol reductase |
Date | Results | Publications |
---|---|---|
2017-10-14 12:57:00 | Dhcr7 heterozygous mice made fewer ultrasonic vocalizations. Increases of 7-DHC and expression of the serotonin transporter were observed in the compound mutant mice. | 28220990 |
2017-01-14 10:43:00 | Studied the effect of 7-dehydrocholesterol reductase (Dhcr7) and identified signal pathways involved in regulation of embryonic palatogenesis. Expression changes of Dhcr7, Sonic Hedgehog (Shh), and bone morphogenetic protein-2 (Bmp2) were measured by RT-PCR and WB after Dhcr7 gene silencing and the addition of exogenous cholesterol. | 27066502 |
2014-08-23 11:20:00 | significant increases in Col1a1, serine/threonine-protein kinase 1, Ctnnb1, CSRNP1, Ddit4, Cyp2e1, and Krit1 expressions and great decreases inreceptor D2, Neu1, and Dhcr7 expressions following long-term exposure to TiO2 NPs | 23533084 |
2013-12-28 11:51:00 | data indicate an underlying dysfunction of the 5-HT2A receptors in Dhcr7-HET mice that warrants further investigation to establish how this may relate to behavioral disturbances in human patients carrying Dhcr7 mutations | 23541496 |
2012-01-14 10:46:00 | conclude that cytochrome P450 reductase is not involved in 7-dehydrocholesterol reductase activity | 21762780 |
Type | IDs |
---|---|
Synonymous | AA409147 |
Gene |
UniProtKB-ID:
DHCR7_MOUSE,
A0A140LIT2_MOUSE
UniprotKB:
O88455,
A0A140LIT2
UniParc:
UPI0005ABB21C,
UPI0000023696
EMBL:
BC006854,
AF057368,
AC133502
Ensembl:
ENSMUSG00000058454
KO:
mmu:13360
|
Nucleutide sequences |
EMBL-CDS:
AAH06854.1,
AAC40164.1
Ensembl_TRS:
ENSMUST00000141916,
ENSMUST00000124340,
ENSMUST00000073878,
ENSMUST00000207143
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000073541,
ENSMUSP00000121782,
ENSMUSP00000117659,
ENSMUSP00000146947
RefSeq:
XP_011240281.1,
NP_001369427.1,
NP_031882.1,
XP_036008532.1,
XP_036008531.1,
NP_001369431.1,
NP_001369432.1,
XP_036008529.1,
XP_030097936.1,
NP_001369430.1,
XP_036008530.1,
XP_036008528.1,
XP_036008527.1,
NP_001369429.1,
XP_006508539.2,
XP_006508541.1,
NP_001369428.1,
XP_036008526.1,
XP_030097935.1
|
Others |
UniRef100:
UniRef100_O88455,
UniRef100_A0A140LIT2
UniRef90:
UniRef90_O88455
UniRef50:
UniRef50_O88455
UniGene:
Mm.249342
CCDS:
CCDS22048.1
|
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