| Type | Description |
|---|---|
| Definition | diacylglycerol O-acyltransferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:21:00 | Lipid-Droplet Formation Drives Pathogenic Group 2 Innate Lymphoid Cells in Airway Inflammation. | 32268121 |
| 2020-02-15 11:53:00 | Hepatic VLDL secretion: DGAT1 determines particle size but not particle number, which can be supported entirely by DGAT2 | 30397187 |
| 2019-10-26 12:05:00 | Study demonstrated that Dgat1-/- mice have alterations in the process of autophagy-mediated cytoplasmic liquid droplets mobilization in enterocytes, likely due to the impairments of autophagic vesicles turnover and lysosome acidification during early stage of dietary fat absorption. | 30342099 |
| 2019-10-12 11:08:00 | Study shows that inactivation of DGAT1 or DGAT2 in adult mouse heart results in a moderate suppression of triglycerides (TG) synthesis and turnover. Partial inhibition of DGAT activity increases cardiac fatty acid oxidation without affecting PPARalpha signaling, myocardial energetics or contractile function. Thus, the two DGAT isoforms in the heart have partially redundant function. | 29563512 |
| 2019-05-04 11:41:00 | hese results demonstrate that DGAT1 suppresses retinol-dependent Treg formation and suggest its potential as a therapeutic target for autoimmune inflammation. | 30718413 |
| Type | IDs |
|---|---|
| Synonymous | ARAT, C75990, D15Ertd23e, Dgat |
| Gene |
UniProtKB-ID:
DGAT1_MOUSE,
Q54AA6_MOUSE
UniprotKB:
Q9Z2A7,
Q54AA6
UniParc:
UPI0000021F43
EMBL:
AB057816,
BC003717,
AF078752,
AK008995
Ensembl:
ENSMUSG00000022555
KO:
mmu:13350
|
| Nucleutide sequences |
EMBL-CDS:
AAC72917.1,
AAH03717.1,
BAC66171.1
Ensembl_TRS:
ENSMUST00000023214
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000023214
RefSeq:
XP_017171915.1,
NP_034176.1,
XP_006520468.1
|
| Others |
UniRef100:
UniRef100_Q9Z2A7
UniRef90:
UniRef90_Q9Z2A7
UniRef50:
UniRef50_Q9Z2A7
UniGene:
Mm.22633
CCDS:
CCDS27573.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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