| Type | Description |
|---|---|
| Definition | desmin |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:14:00 | Desmin is essential for the structure and function of the sinoatrial node: implications for increased arrhythmogenesis. | 32678709 |
| 2019-09-28 11:04:00 | phosphorylation of desmin filaments by GSK3-beta is a key molecular event required for calpain-1-mediated depolymerization, and the subsequent myofibril destruction. | 30061109 |
| 2019-09-21 10:45:00 | In experimental pressure-overload-induced heart failure, toxic cardiac preamyloid oligomers (PAOs) in the myocardium of mice subjected to transverse aortic constriction comigrate with the cytoskeletal protein desmin. There was a 5-fold increase in desmin. Wild-type desmin generates PAOs in cryAB (alpha-B-crystallin) mice. | 29483093 |
| 2018-09-15 11:42:00 | Data suggest that mutated desmin markedly impedes myocyte structure and function at pre-symptomatic stages of myofibrillar myopathies. | 28469177 |
| 2018-04-14 10:05:00 | Moderate MnSOD and/or catalase overexpression in desmin-null hearts leads to a marked decrease in intracellular reactive oxygen species, ameliorates mitochondrial and other ultrastructural defects, minimizes myocardial degeneration and leads to a significant improvement of cardiac function. | 28629836 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
DESM_MOUSE,
Q3V1K9_MOUSE
UniprotKB:
P31001,
Q3V1K9
UniParc:
UPI0000001A91
EMBL:
AK132391,
BC031760,
Z18892,
L22550
Ensembl:
ENSMUSG00000026208
KO:
mmu:13346
|
| Nucleutide sequences |
EMBL-CDS:
AAH31760.1,
CAA79330.1,
BAE21141.1
Ensembl_TRS:
ENSMUST00000027409
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000027409
RefSeq:
NP_034173.1
|
| Others |
UniRef100:
UniRef100_P31001
UniRef90:
UniRef90_P31001
UniRef50:
UniRef50_P08670
UniGene:
Mm.6712
CCDS:
CCDS15071.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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