| Type | Description |
|---|---|
| Definition | solute carrier family 29 (nucleoside transporters), member 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:25:00 | Deletion of equilibrative nucleoside transporter-2 protects against lipopolysaccharide-induced neuroinflammation and blood-brain barrier dysfunction in mice. | 31751618 |
| 2020-07-11 10:10:00 | ENT1/2 chemical inhibition and ENT1 knockout prevented P. aeruginosa-induced lung NLRP3 inflammasome activation. | 31914698 |
| 2020-01-11 10:39:00 | Studies in mice with intestinal mucosa-specific deletion of Ent2 and the A2B receptor demonstrate a significant effect of intestinal epithelial Ent2 inhibition and A2B receptor signaling in protecting the colonic mucosal barrier and suggest that a coordinated network of adenosine transport and signaling between Ent2 and the A2B receptor exists at the epithelial surface that can be pharmacologically targeted in colitis. | 30333323 |
| 2013-12-21 10:35:00 | Data suggest that crosstalk pathway between ENT2 and alveolar epithelial Adora2b in lung protection during acute lung injury (ALI) opens possibilities for combined therapies targeted to this protein set. | 23603835 |
| 2013-10-19 11:21:00 | these findings reveal the transcriptional repression of ENT1,2 as an innate protective response during acute pulmonary inflammation. | 23590299 |
| Type | IDs |
|---|---|
| Synonymous | Der12, Ent2, Hnp36 |
| Gene |
UniProtKB-ID:
S29A2_MOUSE
UniprotKB:
Q61672
UniParc:
UPI000005FBD9
EMBL:
AF183397,
CH466612,
BC048958,
X86682
Ensembl:
ENSMUSG00000024891
KO:
mmu:13340
|
| Nucleutide sequences |
EMBL-CDS:
CAA60381.1,
AAH48958.1,
AAF78477.1,
EDL33088.1
Ensembl_TRS:
ENSMUST00000236152
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000157780
RefSeq:
XP_030106599.1,
XP_030106598.1,
NP_031880.2
|
| Others |
UniRef100:
UniRef100_Q61672
UniRef90:
UniRef90_Q61672
UniRef50:
UniRef50_Q61672
UniGene:
Mm.4930
CCDS:
CCDS50354.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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