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1329 COX5B

1329

COX5B

cytochrome c oxidase subunit 5B

protein-coding

Homo sapiens

基因描述

Type Description
Definition cytochrome c oxidase subunit 5B

研究结论

Date Results Publications
2020-09-12 15:59:00 Systematic expression analysis of the mitochondrial respiratory chain protein subunits identifies COX5B as a prognostic marker in clear cell renal cell carcinoma. 31280487
2018-08-18 11:44:00 Our results suggest that COX5B protein level might be associated with tumor size. COX5B overexpression indicated a worse DFS (p < 0.05) in breast cancer. 28592145
2018-06-16 12:12:00 These experiments suggest that the FAD group of cytochrome b5 reductase increase its solvent exposition upon complex formation promoting an efficient electron transfer between the proteins. 29111436
2016-10-08 12:05:00 silence of COX5B leads to metabolic disorders, such as increased glucose uptake and decreased lactate secretion 26506233
2013-09-28 10:48:00 Transfected the A549 cells with COX Vb small interfering or shRNA and observed a significant reduction of their COX activity, oxygen consumption, ATP and ability to grow in soft agar and as poorly differentiated tumors in athymic mice. 22917272

名称对应

Type IDs
Synonymous COXVB
Gene
UniProtKB-ID: COX5B_HUMAN, A0A384NL93_HUMAN
UniprotKB: P10606, A0A384NL93
UniParc: UPI0000128135
EMBL: BT006742, AC017099, GQ900996, U41284, M59250, BC006229, M19961
Ensembl: ENSG00000135940
KO: hsa:1329
Nucleutide sequences
EMBL-CDS: AAA52060.1, AAH06229.1, AAB19185.1, AAP35388.1, AAY24279.1, AAA52061.1, ADO22513.1
Ensembl_TRS: ENST00000258424
Protein sequencees
Ensembl_PRO: ENSP00000258424
RefSeq: NP_001853.2
Others
UniRef100: UniRef100_P10606
UniRef90: UniRef90_P10606
UniRef50: UniRef50_P10606
UniGene: Hs.1342
CCDS: CCDS2032.1

全选

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研究热度

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