Type | Description |
---|---|
Definition | transmembrane serine protease 11B |
Date | Results | Publications |
---|---|---|
2019-12-14 11:29:00 | These findings establish an oncogenic role for TMPRSS11B and provide support for the development of therapies that target this enzyme at the surface of cancer cells. | 30463017 |
2014-12-06 13:03:00 | Data indicate that TMPRSS11b (BC126195), encoding human airway trypsin-like protease 5 (HATL5), is localized on the cell surface of differentiated epithelial cells in the stratified squamous epithelia of cervix, esophagus, and oral cavity. | 24498351 |
2009-03-25 21:36:00 | Observational study of gene-disease association. (HuGE Navigator) | 19023099 |
2008-12-03 21:30:00 | Observational study of gene-disease association. (HuGE Navigator) | 17975119 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
TM11B_HUMAN
UniprotKB:
Q86T26
UniParc:
UPI000013E249
EMBL:
BC126195,
BX537945,
AK290904,
AC098799,
AL833167
Ensembl:
ENSG00000185873
KO:
hsa:132724
|
Nucleutide sequences |
EMBL-CDS:
AAI26196.1,
BAF83593.1,
CAD91168.1,
CAD97913.1
Ensembl_TRS:
ENST00000332644
|
Protein sequencees |
Ensembl_PRO:
ENSP00000330475
RefSeq:
NP_872308.2,
XP_011529910.1,
XP_011529911.1
|
Others |
UniRef100:
UniRef100_Q86T26
UniRef90:
UniRef90_Q86T26
UniRef50:
UniRef50_Q86T26
UniGene:
Hs.407122
CCDS:
CCDS3521.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
30463017 |
Cell Rep Barrett L Updegraff , Xiaorong Zhou , Yabin Guo , Mahesh S Padanad , Pei-Hsuan Chen , Chendong Yang , Jessica Sudderth , Carla Rodriguez-Tirado , Luc Girard , John D Minna , Prashant Mishra , Ralph J DeBerardinis , Kathryn A O'Donnell |
2018-11-20 | - |
28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
24498351 |
HATL5: a cell surface serine protease differentially expressed in epithelial cancers. PLoS One Gregory S Miller , Gina L Zoratti , Andrew S Murray , Christopher Bergum , Lauren M Tanabe , Karin List |
2014-01-01 | - |
21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
19199708 |
J. Proteome Res. Mireya Gonzalez-Begne , Bingwen Lu , Xuemei Han , Fred K Hagen , Arthur R Hand , James E Melvin , John R Yates |
2009-03-01 |
GNPDA1,
PDCD6IP,
ACTR2,
ADGRG2,
ATP6AP2,
AKR1A1,
ST3GAL6,
CAP1,
VAT1,
HYOU1,
PRDX4,
OLFM4,
CFL1,
CTSC,
MAN1A2,
EHD1,
YWHAQ,
PRSS23,
SLC6A14,
PARK7,
CHST14,
MGAT4A,
TWF2,
C1QTNF3,
SLC26A9,
FAM129A,
CLU,
CLTC,
HIST4H4,
ZG16B,
CNP,
HIST2H3C,
TPRG1L,
COL6A1,
COL6A2,
COPA,
TMPRSS11B,
CPD,
S100A16,
BPIFA2,
A2ML1,
CST3,
CST4,
CST5,
CSTB,
BROX,
CTNNB1,
CTNND1,
PROM2,
CTSB,
PPM1L,
CD55,
DAG1,
GBP6,
AEBP1,
DDX3X,
DEFA1,
DMBT1,
DYNC1H1,
DPP4,
DSC2,
DSG2,
DSP,
TOR1A,
ECM1,
EEF1A1,
EEF2,
KRT78,
ANO6,
ENO1,
ESD,
EVPL,
EXT2,
ALDH1A1,
FAT2,
SLC37A2,
GPC4,
ALDOA,
ERP44,
GANAB,
PLCB1,
FOLR1,
CES3,
PLD3,
FUT2,
FUT3,
FUT6,
FUT8,
NPNT,
PRDX5,
GAPDH,
PHGDH,
B3GAT3,
B4GALT1,
VPS4A,
TOR1B,
GLRX,
AMY1A,
GMDS
|
19023099 |
Gene variants associated with ischemic stroke: the cardiovascular health study. Stroke May M Luke , Ellen S O'Meara , Charles M Rowland , Dov Shiffman , Lance A Bare , Andre R Arellano , W T Longstreth , Thomas Lumley , Kenneth Rice , Russell P Tracy , James J Devlin , Bruce M Psaty |
2009-02-01 |
PGLYRP2,
WDR31,
SLC26A8,
KRT74,
MYOM3,
FCRLB,
TMPRSS11B,
VTI1A,
CYP2C8,
CYP17A1,
DCC,
S1PR1,
F13A1,
FABP2,
FCAR,
KIF6,
COG2,
MYH15,
PALLD,
FSTL4,
DMXL2,
ALOX12B,
TAS2R50,
IL36RN,
GJA4,
GRM8,
HPS1,
SERPINA9,
ITGAE,
KRT5,
RPLP0P4,
OR2A25,
SNX19,
LPA,
MKI67,
MLF1,
OR13G1,
SERPINB8,
PON1,
HEATR5B,
WDR55,
MCM10,
PRKG1,
EIF2AK2,
LGALS14,
LY6G5B,
ROS1,
STRN,
ZNF132,
PRRC2A,
SLC39A7,
CYBRD1,
CALM1,
TAF3,
SGIP1,
IL1F10,
AP3B1,
VAMP8,
AQP10,
P2RX6,
ABCG2,
ADAMTS1,
TOX
|
17975119 |
Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study. Arterioscler Thromb Vasc Biol Dov Shiffman , Ellen S O'Meara , Lance A Bare , Charles M Rowland , Judy Z Louie , Andre R Arellano , Thomas Lumley , Kenneth Rice , Olga Iakoubova , May M Luke , Bradford A Young , Mary J Malloy , John P Kane , Stephen G Ellis , Russell P Tracy , James J Devlin , Bruce M Psaty |
2008-01-01 | - |
16381901 |
Nucleic Acids Res. Alexander Mehrle , Heiko Rosenfelder , Ingo Schupp , Coral del Val , Dorit Arlt , Florian Hahne , Stephanie Bechtel , Jeremy Simpson , Oliver Hofmann , Winston Hide , Karl-Heinz Glatting , Wolfgang Huber , Rainer Pepperkok , Annemarie Poustka , Stefan Wiemann |
2006-01-01 |
AKT3,
ZBTB33,
CMC4,
DNAJB6,
C16orf95,
KIF20A,
ACTR1A,
BCAP31,
FARP1,
LPCAT3,
CDK2,
CDK7,
COQ7,
SPRY2,
STAM2,
CDKN1A,
CDKN1B,
PAK4,
CDKN2B,
RACK1,
IFITM3,
TADA3,
SEMA4F,
SORBS1,
CDC42EP3,
PDLIM5,
ATP5L,
GNB5,
CETN2,
NUDC,
CTSC,
RUVBL2,
SPIN1,
YWHAQ,
ASCC3,
MAPRE2,
SLC38A3,
NUDT21,
C10orf10,
TRIOBP,
PRSS23,
CDC37,
C14orf1,
FAM107A,
POLI,
TREX2,
EGLN2,
USP18,
CHRM2,
COPE,
GABARAPL2,
SYNPO,
ZBED9,
OSBPL5,
GPRASP2,
FCHO2,
DHRS1,
LRRC58,
LYSMD3,
LRRC3B,
RAB39B,
MIA2,
SSX2IP,
GALNT15,
CLCN3,
PIK3AP1,
MORN4,
CLIC2,
TC2N,
ZG16B,
MOB3A,
C19orf47,
LRRC39,
TMEM150A,
BBS5,
PLEKHH2,
OSR1,
COPB1,
SYNPR,
TMPRSS11B,
NUDCD2,
NCOA7,
ZNF786,
MTPN,
ZNF572,
ABRA,
PASD1,
RNF32,
MROH8,
RPL10L,
SRXN1,
CRYAB,
MIB2,
FAM76B,
ZNF664,
CPNE8,
SLFN13,
SCGB1C1,
ZNF555
|
15489336 |
From ORFeome to biology: a functional genomics pipeline. Genome Res. Stefan Wiemann , Dorit Arlt , Wolfgang Huber , Ruth Wellenreuther , Simone Schleeger , Alexander Mehrle , Stephanie Bechtel , Mamatha Sauermann , Ulrike Korf , Rainer Pepperkok , Holger Sültmann , Annemarie Poustka |
2004-10-01 |
AKT3,
ZBTB33,
CMC4,
DNAJB6,
C16orf95,
KIF20A,
ACTR1A,
BCAP31,
FARP1,
LPCAT3,
CDK2,
CDK7,
COQ7,
SPRY2,
STAM2,
CDKN1A,
CDKN1B,
PAK4,
CDKN2B,
RACK1,
IFITM3,
TADA3,
SEMA4F,
SORBS1,
CDC42EP3,
PDLIM5,
ATP5L,
GNB5,
CETN2,
NUDC,
CTSC,
RUVBL2,
SPIN1,
YWHAQ,
ASCC3,
MAPRE2,
SLC38A3,
NUDT21,
C10orf10,
TRIOBP,
PRSS23,
CDC37,
C14orf1,
FAM107A,
POLI,
TREX2,
EGLN2,
USP18,
CHRM2,
COPE,
GABARAPL2,
SYNPO,
ZBED9,
OSBPL5,
GPRASP2,
FCHO2,
DHRS1,
LRRC58,
LYSMD3,
LRRC3B,
RAB39B,
MIA2,
SSX2IP,
GALNT15,
CLCN3,
PIK3AP1,
MORN4,
CLIC2,
TC2N,
ZG16B,
MOB3A,
C19orf47,
LRRC39,
TMEM150A,
BBS5,
PLEKHH2,
OSR1,
COPB1,
SYNPR,
TMPRSS11B,
NUDCD2,
NCOA7,
ZNF786,
MTPN,
ZNF572,
ABRA,
PASD1,
RNF32,
MROH8,
RPL10L,
SRXN1,
CRYAB,
MIB2,
FAM76B,
ZNF664,
CPNE8,
SLFN13,
SCGB1C1,
ZNF555
|
12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
排名 | 科研单位 | 文献 |
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