| Type | Description |
|---|---|
| Definition | cytochrome c oxidase subunit 4I1 |
| Date | Results | Publications |
|---|---|---|
| 2018-11-10 12:00:00 | In case of myocardial insufficiency and dilated cardiomyopathy, decreased expression of COX 4 results in an impaired CytOx activity. Higher enzymatic activity but equal oxygen consumption contribute to the pathophysiology of the myocardial insufficiency and appears as an indicator of oxidative stress. This kind of dysregulation should be in the focus for the development of diagnostic and therapy procedures | 30223867 |
| 2017-12-16 11:00:00 | COX4I1 variant K101N was identified in a patient with short stature, poor weight gain and increased chromosomal breaks, simulating Fanconi anemia. | 28766551 |
| 2017-10-28 13:15:00 | This cohort study showed that the COX411 gene was down regulation between patients with idiopathic Parkinson disease and controls | 28916538 |
| 2015-12-19 10:10:00 | We provide evidence that COX4-1 controls BMI1 expression via a redox mechanism | 25726526 |
| 2013-07-27 12:05:00 | COXIV mRNA (1.6 fold; P<0.01) and COXIV protein expression (1.5 fold; P<0.05) were increased by training but COXIV protein expression was decreased (20%; P<0.01) by acute exercise pre- and post-training. | 23285255 |
| Type | IDs |
|---|---|
| Synonymous | COX IV-1, COX4, COX4-1, COXIV, COXIV-1 |
| Gene |
UniProtKB-ID:
COX41_HUMAN,
H3BNV9_HUMAN,
Q86WV2_HUMAN
UniprotKB:
P13073,
H3BNV9,
Q86WV2
UniParc:
UPI000000DC65,
UPI0000128787,
UPI0001EE936D
EMBL:
BC047869,
BT019825,
BC008704,
AF005889,
AK311847,
X54802,
AF017115,
U90915,
M34600,
BC062437,
M21575,
BC021236,
AC018695,
AH005828,
CH471114
Ensembl:
ENSG00000131143
KO:
hsa:1327
|
| Nucleutide sequences |
EMBL-CDS:
AAB51058.1,
BAG34789.1,
AAA52059.1,
EAW95438.1,
AAH08704.1,
AAB97750.1,
AAC99578.1,
EAW95437.1,
CAA38573.1,
AAH21236.1,
AAA99312.1,
AAH62437.1,
AAV38628.1,
AAB94819.1,
AAH47869.1
Ensembl_TRS:
ENST00000561569,
ENST00000562336,
ENST00000253452,
ENST00000568794,
ENST00000564544
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000457015,
ENSP00000253452,
ENSP00000457513,
ENSP00000455030,
ENSP00000456452
RefSeq:
NP_001305731.1,
NP_001305726.1,
NP_001305717.1,
NP_001305723.1,
NP_001305715.1,
NP_001852.1,
XP_024305924.1
|
| Others |
UniRef100:
UniRef100_P13073,
UniRef100_Q86WV2,
UniRef100_H3BNV9
UniRef90:
UniRef90_P13073,
UniRef90_Q86WV2,
UniRef90_H3BNV9
UniRef50:
UniRef50_H3BNV9,
UniRef50_P13073,
UniRef50_Q95283
UniGene:
Hs.433419
CCDS:
CCDS10955.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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