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132671 SPATA18

132671

SPATA18

spermatogenesis associated 18

protein-coding

Homo sapiens

基因描述

Type Description
Definition spermatogenesis associated 18

研究结论

Date Results Publications
2021-02-27 13:54:00 p53/Mieap-regulated mitochondrial quality control plays an important role as a tumor suppressor in gastric and esophageal cancers. 32736677
2020-12-12 13:27:00 Causative role for defective expression of mitochondria-eating protein in accumulation of mitochondria in thyroid oncocytic cell tumors. 32458504
2020-10-03 12:50:00 Mieap-induced accumulation of lysosomes within mitochondria (MALM) regulates gastric cancer cell invasion under hypoxia by suppressing reactive oxygen species accumulation. 30808977
2020-09-12 16:05:00 DNA damage invokes mitophagy through a pathway involving Spata18. 32453416
2019-01-05 11:28:00 Results show that Mieap induced caspase-dependent mitochondrial apoptosis in breast cancer (BC) cells. Mieap protein was downregulated and its promoter methylated in BC with more aggressive and malignant phenotypes. 30290054

名称对应

Type IDs
Synonymous Mieap, SPETEX1
Gene
UniProtKB-ID: MIEAP_HUMAN, A0A140VKF4_HUMAN
UniprotKB: Q8TC71, A0A140VKF4
UniParc: UPI0000E08EC2, UPI000006FB0D
EMBL: BC025396, AB465501, AC093858, AK098625, HM005694, BC037886, AB465502, AK304386, CH471057
Ensembl: ENSG00000163071
KO: hsa:132671
Nucleutide sequences
EMBL-CDS: BAJ53738.1, BAG65222.1, BAJ53739.1, BAC05356.1, EAX05433.1, AAH37886.1, AAH25396.1, AEE61291.1
Ensembl_TRS: ENST00000419395, ENST00000295213
Protein sequencees
Ensembl_PRO: ENSP00000295213, ENSP00000415309
RefSeq: NP_001284537.1, XP_005265774.1, XP_011532672.1, NP_001333032.1, XP_011532671.1, NP_001333031.1, XP_011532674.1, NP_660306.1, XP_024309659.1, XP_016863220.1
Others
UniRef100: UniRef100_Q8TC71
UniRef90: UniRef90_Q8TC71
UniRef50: UniRef50_Q8TC71
UniGene: Hs.527090
CCDS: CCDS75124.1, CCDS3489.1

全选

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