| Type | Description |
|---|---|
| Definition | mitogen-activated protein kinase kinase kinase 8 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:07:00 | Melanocytic tumors with MAP3K8 fusions: report of 33 cases with morphological-genetic correlations. | 31719662 |
| 2021-02-13 13:25:00 | TPL2 enforces RAS-induced inflammatory signaling and is activated by point mutations. | 32573499 |
| 2021-02-06 13:50:00 | ATF-2 and Tpl2 regulation of endothelial cell cycle progression and apoptosis. | 31760171 |
| 2020-12-12 13:29:00 | Her2 promotes early dissemination of breast cancer by suppressing the p38 pathway through Skp2-mediated proteasomal degradation of Tpl2. | 32989258 |
| 2020-09-19 10:16:00 | The increased inflammation of Map3k8(-/-) mice in allergic airway inflammation and colitis results from reduced ABIN-2 signaling, rather than blocked TPL-2 signaling. | 31401161 |
| Type | IDs |
|---|---|
| Synonymous | AURA2, COT, EST, ESTF, MEKK8, TPL2, Tpl-2, c-COT |
| Gene |
UniProtKB-ID:
M3K8_HUMAN,
Q6FG25_HUMAN
UniprotKB:
P41279,
Q6FG25
UniParc:
UPI000013D395,
UPI00003B5D4C,
UPI000017C34B
EMBL:
AF133211,
AK290320,
AY309013,
D14497,
CH471072,
Z14138,
CR542284,
AL161651,
BC113566,
BC104833
Ensembl:
ENSG00000107968
KO:
hsa:1326
|
| Nucleutide sequences |
EMBL-CDS:
EAW86004.1,
BAA03387.1,
AAI13567.1,
AAI04834.1,
EAW86006.1,
AAG13454.1,
EAW86005.1,
CAA78512.1,
BAF83009.1,
EAW86007.1,
AAP45053.1,
CAG47079.1
Ensembl_TRS:
ENST00000542547,
ENST00000375321,
ENST00000263056
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000364470,
ENSP00000443610,
ENSP00000263056
RefSeq:
XP_016871202.1,
XP_016871197.1,
XP_016871201.1,
XP_016871199.1,
XP_016871200.1,
NP_001307890.1,
XP_016871198.1,
NP_005195.2,
NP_001231063.1,
XP_024303587.1,
XP_016871203.1
|
| Others |
UniRef100:
UniRef100_P41279,
UniRef100_Q6FG25
UniRef90:
UniRef90_P41279
UniRef50:
UniRef50_P41279
UniGene:
Hs.432453,
Hs.731448
CCDS:
CCDS7166.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员