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13244 Degs1

13244

Degs1

delta(4)-desaturase, sphingolipid 1

protein-coding

Mus musculus

基因描述

Type Description
Definition delta(4)-desaturase, sphingolipid 1

研究结论

Date Results Publications
2020-05-16 10:30:00 Des1 expression in Muller cells is not required for cone visual pigment regeneration in the mouse. 30645148
2020-03-28 11:28:00 These studies suggest that inhibition of DES1 may provide a means of treating hepatic steatosis and metabolic disorders 31273070
2019-03-16 12:16:00 Biochemical assays, cellular lipid feeding experiments, and pharmacological blockade of ceramide synthase (dihydroceramide desaturase) together show that this enzyme indeed controls the flux of ceramides on maturing phagosomes. 29963848
2015-05-23 12:57:00 genetic ablation of DEGS1 in preadipocytes prevented adipogenesis and decreased lipid accumulation. This was associated with elevated oxidative stress, cellular death, and blockage of the cell cycle. 25352638
2013-08-31 10:16:00 The role of Degs1 in the hypoxic mouse heart.Hand2 and NFATC physically interact on the DEGS1 promoter. 23672204

名称对应

Type IDs
Synonymous AA536663, Degs, Des1, Mdes
Gene
UniProtKB-ID: DEGS1_MOUSE
UniprotKB: O09005
UniParc: UPI0000023B70
EMBL: AK163404, AK077257, AF466376, AK002617, AK149811, Y08460, BC003751
Ensembl: ENSMUSG00000038633
KO: mmu:13244
Nucleutide sequences
EMBL-CDS: BAE29098.1, AAM12532.1, AAH03751.1, BAE37337.1, CAA69714.1, BAC36713.1, BAB22233.1
Ensembl_TRS: ENSMUST00000035295
Protein sequencees
Ensembl_PRO: ENSMUSP00000048519
RefSeq: NP_001347712.1, NP_031879.1
Others
UniRef100: UniRef100_O09005
UniRef90: UniRef90_O09005
UniRef50: UniRef50_O09005
UniGene: Mm.29648
CCDS: CCDS15587.1

全选

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研究热度

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