| Type | Description |
|---|---|
| Definition | defensin, alpha, 4 |
| Date | Results | Publications |
|---|---|---|
| 2017-09-09 13:05:00 | Depleting CRP4 is incompatible with a proper cardiac development and function. CRP4 is a novel antiremodeling factor regulated, at least to some extent, by cardiac cGMP. | 28138039 |
| 2012-01-28 12:10:00 | Backbone cyclization provides a means for engineeringalpha-defensins to improve their biological activity while providing excellent stability to serum degradation and highlighting the potential of peptide scaffolds for development of novel compounds. | 22040603 |
| 2011-08-20 10:10:00 | bactericidal activity predominantly affects noncommensal bacteria | 21099205 |
| 2010-01-21 00:00:00 | Crp4 disulfide arrangement confers essential protection from degradation by this critical activating proteinase, allowing antibacterial action. | 15297466 |
| 2010-01-21 00:00:00 | function of the conserved salt bridge in Crp4 is not linked to bactericidal activity or proteolytic stability of the mature peptide. | 16857681 |
| Type | IDs |
|---|---|
| Synonymous | Crp4, Defa28, Defcr4 |
| Gene |
UniProtKB-ID:
DEFA4_MOUSE
UniprotKB:
P28311
UniParc:
UPI00000282B1
EMBL:
AF178040,
U03032,
BC134360
KO:
mmu:13238
|
| Nucleutide sequences |
EMBL-CDS:
AAI34361.1,
AAD51759.1,
AAA57172.1
|
| Protein sequencees |
RefSeq:
NP_034169.2
|
| Others |
UniRef100:
UniRef100_P28311
UniRef90:
UniRef90_P28311
UniRef50:
UniRef50_P28311
UniGene:
Mm.465152
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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