| Type | Description |
|---|---|
| Definition | defensin, alpha, 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-05-04 11:48:00 | we engineered a monoclonal antibody against HNP-1 to block the interaction with P2X7 and found that the blocking antibody protected mice carrying high copy number of DEFA1/DEFA3 from lethal sepsis. We thus demonstrate that DEFA1/DEFA3 copy number variation strongly modulates sepsis development in vivo and explore a paradigm for the precision treatment of sepsis tailored by individual genetic information. | 30718392 |
| 2010-01-21 00:00:00 | cryptdin 3 forms anion-selective channels on the cytoplasmic membrane of HEK cells and that the kinetics of one such channel are affected by its interaction with other such channels. | 11960772 |
| 2010-01-21 00:00:00 | MMP-7-dependent procryptdin activation in vivo provides mouse Paneth cells with functional peptides for apical secretion into the small intestine lumen | 11733520 |
| Type | IDs |
|---|---|
| Synonymous | Defa27, Defcr-3, Defcr3 |
| Gene |
UniProtKB-ID:
DEFA3_MOUSE
UniprotKB:
P28310
UniParc:
UPI00000282B0
EMBL:
U02999,
U02998,
BC099855,
U03030,
U12559
Ensembl:
ENSMUSG00000060208,
ENSMUSG00000074440
KO:
mmu:23855,
mmu:13237
|
| Nucleutide sequences |
EMBL-CDS:
AAA57171.1,
AAA20972.1,
AAH99855.1,
AAB60677.1
Ensembl_TRS:
ENSMUST00000098893,
ENSMUST00000079528
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000078485,
ENSMUSP00000096492
RefSeq:
NP_031876.1
|
| Others |
UniRef100:
UniRef100_P28310
UniRef90:
UniRef90_P50704
UniRef50:
UniRef50_P50704
UniGene:
Mm.436573
CCDS:
CCDS40270.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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