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13214 Defb1

13214

Defb1

defensin beta 1

protein-coding

Mus musculus

基因描述

Type Description
Definition defensin beta 1

研究结论

Date Results Publications
2020-03-28 10:52:00 Results found that Foxa2 is involved in the transcriptional regulation of DEFB1, and downregulation of DEFB1 due to suppression of Foxa2 expression is likely to contribute to increased infection risk in the Th2-dominated airway inflammation. 31881038
2016-03-05 11:23:00 Fenofibrate and gemfibrozil inhibit LPS-induced inflammatory activation of macrophages via PPARalpha/beta-defensin 1/TLR4 pathway. 25881202
2015-04-25 11:33:00 these studies demonstrate a role for the murine beta-defensin 1 peptide in early control of Candida infection in a murine model of mucosal candidiasis 25595775
2011-12-03 11:22:00 Akt1 is involved in the regulation of defensin expression and the innate immune response important for bacterial clearance 21559496
2011-10-15 11:29:00 Histopathology showed a greater inflammatory influx in the lungs of mBD-1((-/-)) mice at Day 3 postinfection compared with WT C57BL/6 mice 21551252

名称对应

Type IDs
Synonymous AW260221, BD-1
Gene
UniProtKB-ID: DEFB1_MOUSE, Q3UQE2_MOUSE
UniprotKB: P56386, Q3UQE2
UniParc: UPI00000019DC
EMBL: AA071757, AA107538, AK142544, AA065510, BC024380, AF003524, AA105324, AF003525, AA108061
Ensembl: ENSMUSG00000044748
KO: mmu:13214
Nucleutide sequences
EMBL-CDS: AAH24380.1, AAB72003.1, BAE25100.1
Ensembl_TRS: ENSMUST00000051017
Protein sequencees
Ensembl_PRO: ENSMUSP00000051754
RefSeq: NP_031869.1
Others
UniRef100: UniRef100_P56386
UniRef90: UniRef90_P56386
UniRef50: UniRef50_P56386
UniGene: Mm.431316
CCDS: CCDS40282.1

全选

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研究热度

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