| Type | Description |
|---|---|
| Definition | DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 10:27:00 | DDX6-null germ cells exhibited both similar and distinct defects from those observed in NANOS2-null germ cells. These results demonstrate that NANOS2 function is carried out via both P-body-dependent and -independent mechanisms. RNA-seq analyses further supported the phenotypic differences between DDX6-null and NANOS2-null germ cells, and indicated distinct molecular cascades involved in NANOS2-mediated gene regulation. | 30679547 |
| 2020-05-23 10:10:00 | DDX6 is required for maintaining the quiescent state of primordial follicles. | 31657143 |
| 2018-12-22 11:35:00 | The Ddx6 knockout cells were phenotypically and molecularly similar to cells lacking all microRNAs (Dgcr8 knockout ESCs). These data show that the loss of DDX6 can separate the two canonical functions of microRNAs: translational repression and transcript destabilization | 30044225 |
| 2015-06-27 10:22:00 | Data show that RNA helicase DDX6 colocalizes with ubiquitin-protein ligase TRIM32 in neural stem cells and neurons and that it increases the activity of microRNA Let-7a. | 25722370 |
| 2010-01-21 00:00:00 | rck/p54 may play an important role in gametogenesis and early embryogenesis in mammals | 15906376 |
| Type | IDs |
|---|---|
| Synonymous | 1110001P04Rik, C430015D01Rik, E230023J21Rik, HLR2, mRCK/P54, p54, rck |
| Gene |
UniProtKB-ID:
DDX6_MOUSE
UniprotKB:
P54823
UniParc:
UPI00000019A8
EMBL:
AF038995,
BC021452,
AK148483,
AK054144,
D50494
Ensembl:
ENSMUSG00000032097
KO:
mmu:13209
|
| Nucleutide sequences |
EMBL-CDS:
BAC35670.1,
BAA09088.1,
AAB94769.1,
BAE28578.1,
AAH21452.1
Ensembl_TRS:
ENSMUST00000170489,
ENSMUST00000217034
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000149620,
ENSMUSP00000128421
RefSeq:
XP_011240693.1,
NP_001344632.1,
NP_031867.1,
XP_030099902.1,
NP_851841.2,
NP_001104296.1,
NP_001344631.1
|
| Others |
UniRef100:
UniRef100_P54823
UniRef90:
UniRef90_P26196
UniRef50:
UniRef50_P26196
UniGene:
Mm.267061
CCDS:
CCDS23116.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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