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13205 Ddx3x

13205

Ddx3x

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked

protein-coding

Mus musculus

基因描述

Type Description
Definition DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked

研究结论

Date Results Publications
2021-02-02 13:26:00 DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma. 32553121
2020-04-04 11:13:00 The stress granule protein DDX3X interacts with NLRP3 to drive inflammasome activation 31511697
2020-02-01 11:24:00 Loss of Ddx3x led to decreased levels of DNA repair factors, which contributed to an accumulation of unrepaired DNA damage, replication stress, and eventually, spontaneous liver tumors and DEN-induced HCCs in Alb-Cre/+;Ddx3x(flox/flox) mice. 30297359
2019-08-31 13:33:00 Ddx3x and Ddx3y are dispensable for spermatogenesis at least in mice. Unlike human, mice have an additional Ddx3y paralog D1pas1, that has been reported to be essential for spermatogenesis. Human and mouse DDX3 related proteins have distinct differences in their functions. 30613052
2019-05-11 10:56:00 DDX3X is a substrate of both HDAC6 catalytic domains.DDX3X-intrinsically disordered region 1 is important for the stress granules formation. 30531905

名称对应

Type IDs
Synonymous D1Pas1-rs2, Ddx3, Fin14
Gene
UniProtKB-ID: DDX3X_MOUSE, Q3TQX5_MOUSE, B7ZWF1_MOUSE
UniprotKB: Q62167, Q3TQX5, B7ZWF1
UniParc: UPI0000044D80, UPI000189A9DD
EMBL: AK140990, BC172016, AK163250, L25126, Z38117
Ensembl: ENSMUSG00000000787
KO: mmu:13205
Nucleutide sequences
EMBL-CDS: AAA53630.1, CAA86261.1, BAE37257.1, BAE24540.1, AAI72016.1
Ensembl_TRS: ENSMUST00000000804
Protein sequencees
Ensembl_PRO: ENSMUSP00000000804
RefSeq: NP_034158.1
Others
UniRef100: UniRef100_Q62167, UniRef100_B7ZWF1
UniRef90: UniRef90_O00571, UniRef90_P16381
UniRef50: UniRef50_O00571
UniGene: Mm.289662
CCDS: CCDS30027.1

全选

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