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13200 Ddost

13200

Ddost

dolichyl-di-phosphooligosaccharide-protein glycotransferase

protein-coding

Mus musculus

基因描述

Type Description
Definition dolichyl-di-phosphooligosaccharide-protein glycotransferase

研究结论

Date Results Publications
2020-10-31 13:18:00 Globally elevating the AGE clearance receptor, OST48, does not protect against the development of diabetic kidney disease, despite improving insulin secretion. 31541173
2019-07-20 12:40:00 Study demonstrated that dolichyl-diphosphooligosaccharide-protein glycosyltransferase Ost48 (encoded by Ddost gene) is a facilitator of increased advanced glycation end-products (AGE) deposition in the liver and OST48-AGE pathway leads to the onset of liver injury in combination with central adiposity and glucose intolerance, despite ample physical activity. 28947796
2017-11-25 13:19:00 the cell-cycle-dependent post-translation modification of TREX1 regulates its interaction with OST. 28297665
2016-01-16 10:10:00 Data show that oligosaccharyltransferase (OST) activity is dysregulated in three prime exonuclease 1 knockout (Trex1-/-) cells. 26320659
2010-04-12 12:17:00 AGER1 provides protection against AGE-induced reactive oxygen species generation via NADPH oxidase and protein kinase C delta. 19955485

名称对应

Type IDs
Gene
UniProtKB-ID: OST48_MOUSE
UniprotKB: O54734
UniParc: UPI00000E9D86
EMBL: D89063, AK081542, AL807249, AB012717, BC068132
Ensembl: ENSMUSG00000028757
KO: mmu:13200
Nucleutide sequences
EMBL-CDS: BAA23671.1, AAH68132.1, BAC38250.1, BAB82434.1
Ensembl_TRS: ENSMUST00000030538
Protein sequencees
Ensembl_PRO: ENSMUSP00000030538
RefSeq: NP_031864.2
Others
UniRef100: UniRef100_O54734
UniRef90: UniRef90_P39656-3
UniRef50: UniRef50_P39656-3
UniGene: Mm.7236, Mm.470295
CCDS: CCDS18824.1

全选

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研究热度

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