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13191 Dctn1

13191

Dctn1

dynactin 1

protein-coding

Mus musculus

基因描述

Type Description
Definition dynactin 1

研究结论

Date Results Publications
2018-12-22 11:31:00 that a single mutation in the DCTN1 gene recapitulates symptoms of Perry syndrome patients 29273399
2018-11-10 12:20:00 our findings demonstrate that p150(Glued) is particularly required to maintain the function and survival of spinal motor neurons during aging 29490687
2018-08-25 10:41:00 p75NTR intracellular domain as a retrograde degenerative signal and reveal p150(Glued) deacetylation as a unique mechanism regulating axonal transport 30086304
2016-02-06 10:28:00 a mouse model expressing disease linked-G59S mutant dynactin p150(Glued) develops motor dysfunction >8 months before loss of motor neurons or dopaminergic degeneration is observed. 25552654
2015-10-24 10:31:00 These findings uncovered the surprising functional relevance of GTP-bound Arl3 and LC8 for the unloading regulation of dynactin-bound cargo from dynein motor. 25342295

名称对应

Type IDs
Synonymous AL022633, DAP-150, DP-150, Glued, p150, p150-glued, p150
Gene
UniProtKB-ID: DCTN1_MOUSE, E9Q3M3_MOUSE, D3YX34_MOUSE, Q6NZM3_MOUSE, Q3TRF1_MOUSE, E9Q586_MOUSE
UniprotKB: O08788, E9Q3M3, D3YX34, Q6NZM3, Q3TRF1, E9Q586
UniParc: UPI00005B1ED8, UPI00015AA42F, UPI00015AA439, UPI000023B758, UPI00015AA438, UPI00003573DC, UPI0000597564
EMBL: U60312, BC066061, AK162846, AK157867, AC160400
Ensembl: ENSMUSG00000031865
KO: mmu:13191
Nucleutide sequences
EMBL-CDS: AAB57773.1, BAE34241.1, AAH66061.1, BAE37079.1
Ensembl_TRS: ENSMUST00000113919, ENSMUST00000113918, ENSMUST00000113913, ENSMUST00000113907, ENSMUST00000077407
Protein sequencees
Ensembl_PRO: ENSMUSP00000109551, ENSMUSP00000109552, ENSMUSP00000109546, ENSMUSP00000109540, ENSMUSP00000076623
RefSeq: XP_006505553.1, XP_006505556.1, XP_006505554.1, XP_006505555.1, XP_017176868.1, XP_030110997.1, NP_001185795.1, XP_006505552.1, XP_006505550.1, XP_036021693.1, XP_006505551.1, XP_030110996.1, XP_006505558.1, XP_030110995.1, NP_001185796.1, NP_001334239.1, XP_006505559.1, NP_031861.2, XP_006505549.1, XP_036021695.1, XP_006505548.1, XP_006505557.1
Others
UniRef100: UniRef100_Q6NZM3, UniRef100_O08788, UniRef100_D3YX34, UniRef100_E9Q586
UniRef90: UniRef90_Q14203-6, UniRef90_Q14203-2
UniRef50: UniRef50_Q14203, UniRef50_Q14203-2
UniGene: Mm.6919
CCDS: CCDS39532.1

全选

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