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13178 Dck

13178

Dck

deoxycytidine kinase

protein-coding

Mus musculus

基因描述

Type Description
Definition deoxycytidine kinase

研究结论

Date Results Publications
2015-04-25 10:04:00 Mutation of a single serine 74 residue has profound effects on murine T and B lymphocyte development, suggesting that post-translational regulation of dCK has a role in maintaining genomic stability during hematopoiesis. 25101980
2013-07-06 11:49:00 activating the dAdo-DCK-dATP pathway directly results in increased apoptosis in the lungs of mice with air-space enlargement and suggests a novel therapeutic target for the treatment of COPD 23392349
2012-06-23 12:12:00 Deoxycytidine kinase is a new regulator of hematopoietic integrity and lymphocyte quiescence and survival. 22407915
2010-04-19 11:22:00 The severe impact of dCK inactivation on lymphopoiesis was unexpected given that nucleoside salvage has been thought to play a limited, "fine-tuning" role in regulating deoxyribonucleotide triphosphate pools produced by the de novo pathway. 20080663

名称对应

Type IDs
Gene
UniProtKB-ID: DCK_MOUSE, Q545E8_MOUSE
UniprotKB: P43346, Q545E8
UniParc: UPI0000003E87
EMBL: AK145390, X77731, AK048347, BC060062, AF260315, AK151851, AK088195, AK004592, AK010700, AK145353
Ensembl: ENSMUSG00000029366
KO: mmu:13178
Nucleutide sequences
EMBL-CDS: AAG53743.1, CAA54787.1, AAH60062.1, BAB27131.1, BAC40203.1, BAC33307.1, BAE26407.1, BAE26382.1, BAE30741.1, BAB23394.1
Ensembl_TRS: ENSMUST00000031311
Protein sequencees
Ensembl_PRO: ENSMUSP00000031311
RefSeq: NP_031858.1
Others
UniRef100: UniRef100_P43346
UniRef90: UniRef90_P27707
UniRef50: UniRef50_P27707
UniGene: Mm.298892
CCDS: CCDS19405.1

全选

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研究热度

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