| Type | Description |
|---|---|
| Definition | Fas death domain-associated protein |
| Date | Results | Publications |
|---|---|---|
| 2020-06-13 12:23:00 | human HSP27 enhanced stat3 activity to increase Daxx transcription. Interestingly, human Daxx, but not mouse Daxx, was degraded as normal by ubiquitin-dependent lysosomal degradation; however, HSP27 downregulation induced the ubiquitin-independent proteasomal degradation of Daxx. | 31615977 |
| 2019-08-03 12:10:00 | the data support a tumor suppressor role for DAXX as low-dose ionizing radiation produced a higher proportion of carcinomas in Daxx heterozygous mice than wild-type controls. While DAXX has important in vivo functions, they are independent of an inhibitory role on the p53 tumor suppressor pathway. | 29903771 |
| 2019-06-29 10:28:00 | A lncRNA ChRO1 specifically associates with ATRX/DAXX/H3.3 complex at chromocenters to promote H3.3 incorporation and transcriptional induction of satellite repeats, which is essential for chromocenter clustering thus unveiling a mechanism involving a lncRNA that plays a role in large-scale heterochromatin reorganization and cell differentiation. | 30335163 |
| 2019-04-20 12:42:00 | DAXX plays an important role in cisplatin resistance in ovarian cancer | 29906705 |
| 2018-12-29 12:01:00 | DAXX can induce ovarian cancer ascites formation by activating the ERK signal pathway and binding to CEBP-beta. | 30336783 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
DAXX_MOUSE,
Q3UKR0_MOUSE
UniprotKB:
O35613,
Q3UKR0
UniParc:
UPI00000299C5,
UPI000016C893
EMBL:
AK133863,
CR974462,
AF006040,
AF100956,
AK153149,
AK145906,
AF110520
Ensembl:
ENSMUSG00000002307
KO:
mmu:13163
|
| Nucleutide sequences |
EMBL-CDS:
AAC69891.1,
AAC97971.1,
AAC53284.1,
BAE31759.1,
BAE21895.1,
BAE26741.1
Ensembl_TRS:
ENSMUST00000170075,
ENSMUST00000079421
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000128504,
ENSMUSP00000078390
RefSeq:
XP_006523644.1,
NP_001186662.1,
NP_001342633.1,
NP_031855.3,
XP_006523645.1
|
| Others |
UniRef100:
UniRef100_O35613,
UniRef100_Q3UKR0
UniRef90:
UniRef90_O35613
UniRef50:
UniRef50_Q9UER7
UniGene:
Mm.271809
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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