| Type | Description |
|---|---|
| Definition | tripartite motif containing 71 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-22 15:29:00 | Ubiquitin ligase TRIM71 suppresses ovarian tumorigenesis by degrading mutant p53. | 31570706 |
| 2020-06-06 11:14:00 | TRIM71-mediated target recognition and repression mechanisms uncovers a role for this stem cell-specific factor and oncogene in non-canonical Nonsense-mediated Decay (NMD), revealing the existence of a novel mRNA surveillance mechanism which has been termed here the TRIM71/NMD axis. | 31732746 |
| 2019-11-02 11:04:00 | TRIM71 mutations implicated in etiogenesis of human congenital hydrocephalus impair target silencing | 31371437 |
| 2018-02-17 11:02:00 | TRIM71 acts through post-transcriptional repression of Lin28B and subsequent modulation of let-7-HMGA2 signaling during tumorigenesis to potentially function as a tumor suppressor. | 27821801 |
| 2016-10-01 11:16:00 | Studies indicate most-studied TRIpartite Motif (TRIM)-NHL proteins TRIM2, TRIM3, TRIM32 and TRIM71, and their mutations have been linked to diseases. | 26514622 |
| Type | IDs |
|---|---|
| Synonymous | LIN-41, LIN41 |
| Gene |
UniProtKB-ID:
LIN41_HUMAN
UniprotKB:
Q2Q1W2
UniParc:
UPI000067CB89
EMBL:
DQ232881
Ensembl:
ENSG00000206557
KO:
hsa:131405
|
| Nucleutide sequences |
EMBL-CDS:
ABB18374.1
Ensembl_TRS:
ENST00000383763
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000373272
RefSeq:
NP_001034200.1
|
| Others |
UniRef100:
UniRef100_Q2Q1W2
UniRef90:
UniRef90_Q2Q1W2
UniRef50:
UniRef50_Q1PSW8
UniGene:
Hs.567678
CCDS:
CCDS43060.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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