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13138 Dag1

13138

Dag1

dystroglycan 1

protein-coding

Mus musculus

基因描述

Type Description
Definition dystroglycan 1

研究结论

Date Results Publications
2020-04-25 11:58:00 beta-dystroglycan intracellular domain acts as negative regulator of rDNA transcription by impeding the transcriptional activity of UBF, as a part of the protective mechanism activated in response to nucleolar stress 30814495
2020-04-11 10:06:00 These findings establish Dystroglycan as a multifunctional scaffold that coordinates extracellular matrix proteins, secreted cues, and transmembrane receptors to regulate axon guidance. 30758284
2019-11-02 10:11:00 Our data suggest a mechanism where dystroglycan-mediated signaling between the cell and the extracellular matrix controls the proliferative potential of progenitors in the developing retina 29853630
2018-12-01 11:16:00 alpha-DG hypoglycosylation, together with an increased protein instability, reduces the membrane dynamics of the beta-subunit and its clustering within the actin-rich domains, influencing cell migration and spontaneous cell movement. 28572004
2018-03-17 11:15:00 Utrn KO mdx mice but not mdx mice show decreased expression of serum N-terminal alpha Dystroglycan compared to normal mice. 27854211

名称对应

Type IDs
Synonymous D9Wsu13e, DG, Dp427, Dp71
Gene
UniProtKB-ID: DAG1_MOUSE, Q8BPJ7_MOUSE, Q8CBE6_MOUSE, Q544G5_MOUSE
UniprotKB: Q62165, Q8BPJ7, Q8CBE6, Q544G5
UniParc: UPI00000018B8, UPI00000E94ED, UPI00000EB082
EMBL: U48854, BC007150, AK038702, AK036174, AK053886, Z34532, X86073, U43512
Ensembl: ENSMUSG00000039952
KO: mmu:13138
Nucleutide sequences
EMBL-CDS: AAC52853.1, CAA60031.1, CAA84293.1, AAH07150.1, AAA99779.2, BAC35576.1, BAC29332.1, BAC30105.1
Ensembl_TRS: ENSMUST00000166905, ENSMUST00000171412, ENSMUST00000191899, ENSMUST00000080435
Protein sequencees
Ensembl_PRO: ENSMUSP00000142109, ENSMUSP00000079294, ENSMUSP00000130626, ENSMUSP00000128531
RefSeq: NP_001263415.1, XP_030099901.1, NP_001263411.1, NP_034147.1, NP_001263410.1, NP_001263422.1, XP_030099900.1, NP_001263421.1, NP_001263414.1, XP_006511699.1
Others
UniRef100: UniRef100_Q8BPJ7, UniRef100_Q62165, UniRef100_Q8CBE6
UniRef90: UniRef90_Q14118
UniRef50: UniRef50_Q14118
UniGene: Mm.7524, Mm.491797
CCDS: CCDS23518.1

全选

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