| Type | Description |
|---|---|
| Definition | cytochrome P450, family 8, subfamily b, polypeptide 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-02-23 10:40:00 | The altered bile acid composition of Cyp8b1(-/-) mice preserves metabolic and respiratory function by repressing hepatic lipogenesis and driving favorable changes in gut antimicrobial responses. | 29066462 |
| 2017-09-09 11:33:00 | Cyp8b1(-/-) mice were resistant to Western diet-induced body weight gain, hepatic steatosis, and insulin resistance. | 28377401 |
| 2015-05-23 11:49:00 | Absence of Cyp8b1 results in improved glucose tolerance, insulin sensitivity, and beta-cell function, mediated by absence of cholic acid in Cyp8b1(-/-) mice. | 25338812 |
| 2014-04-26 10:08:00 | Cholesterol lowering properties of oats involve increased production of bile acids via the classic pathway with up-regulation of CYP7A1 and CYP8B1. | 23262749 |
| 2014-02-22 10:09:00 | RORalpha is a key regulator of diurnal rhythm and fasting induction of CYP8B1, which regulates bile acid composition and serum and liver cholesterol levels. | 24226095 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CP8B1_MOUSE,
A0A0R4J0N7_MOUSE
UniprotKB:
O88962,
A0A0R4J0N7
UniParc:
UPI00000257EF,
UPI00000018F9
EMBL:
BC010973,
AF090317,
AF090319,
BC049969,
BC010974,
AC164092
Ensembl:
ENSMUSG00000050445
KO:
mmu:13124
|
| Nucleutide sequences |
EMBL-CDS:
AAC63036.1,
AAH10974.1,
AAH49969.1,
AAH10973.1,
AAD19876.1
Ensembl_TRS:
ENSMUST00000062474
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000052989
RefSeq:
NP_034142.3
|
| Others |
UniRef100:
UniRef100_A0A0R4J0N7,
UniRef100_O88962
UniRef90:
UniRef90_O88962
UniRef50:
UniRef50_Q9UNU6
UniGene:
Mm.20889
CCDS:
CCDS23641.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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