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13123 Cyp7b1

13123

Cyp7b1

cytochrome P450, family 7, subfamily b, polypeptide 1

protein-coding

Mus musculus

基因描述

Type Description
Definition cytochrome P450, family 7, subfamily b, polypeptide 1

研究结论

Date Results Publications
2019-11-23 10:47:00 This study provides evidence for CYP7B1 as a key regulator of three vital intracellular regulatory oxysterol levels. 30710743
2019-07-27 11:02:00 results indicate that osteoarthritis is a disease associated with metabolic disorders and suggest that targeting the CH25H-CYP7B1-RORalpha axis of cholesterol metabolism may provide a therapeutic avenue for treating osteoarthritis. 30728500
2012-12-22 10:46:00 Findings indicate that CYP7B1 and HSD3B7, as well as CH25H, have essential roles in controlling oxysterol production in lymphoid tissues. 22999953
2010-09-13 11:17:00 Increasing 27-hydroxycholesterol concentrations by genetic means leads to decrease bone mineral density. 20501668
2010-01-21 00:00:00 Identification of Cyp7b1 as a novel RORalpha (NR1F1) target gene and a functional cross-talk between RORalpha and liver X receptor (NR1H3). 18055760

名称对应

Type IDs
Synonymous AW261589, D3Ertd552e, hct-1
Gene
UniProtKB-ID: CP7B1_MOUSE, Q3USU4_MOUSE
UniprotKB: Q60991, Q3USU4
UniParc: UPI00005ABF71, UPI00000E7D02
EMBL: AK140100, AK013034, U36993
Ensembl: ENSMUSG00000039519
KO: mmu:13123
Nucleutide sequences
EMBL-CDS: BAB28613.1, AAA92615.1, BAE24236.1
Ensembl_TRS: ENSMUST00000035625
Protein sequencees
Ensembl_PRO: ENSMUSP00000037487
RefSeq: XP_006535447.1, NP_031851.3, XP_006535446.1
Others
UniRef100: UniRef100_Q60991, UniRef100_Q3USU4
UniRef90: UniRef90_Q60991
UniRef50: UniRef50_Q60991
UniGene: Mm.316000
CCDS: CCDS17254.1

全选

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研究热度

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