| Type | Description |
|---|---|
| Definition | cytochrome P450, family 7, subfamily a, polypeptide 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-08-18 12:05:00 | vitamin D-deficiency resulted in down-regulation of liver Cyp7a1 and renal Oat3, conditions that are alleviated upon replenishment of cholecalciferol. | 29243851 |
| 2018-03-31 11:50:00 | Hypercholesterolemia in TALLYHO/jng mice might increase the Bile acids amounts via the interrupted Fxr/Fgf15/Fgfr4-mediated feedback regulation of Cyp7a1. | 28843503 |
| 2017-09-02 12:42:00 | although feeding LS-Xbp1(-/-) mice cholesterol did not increase CYP7A1 expression, serum C4 levels increased significantly up to levels similar to chow-fed Xbp1(fl/fl) mice and the total bile acid pool normalized. In conclusion, loss of hepatic XBP1 decreased the bile acid pool and CYP7A1 synthetic activity. | 28039331 |
| 2017-08-26 12:56:00 | Cyp7a1(-/-) mice have improved glucose sensitivity with reduced liver triglycerides and fecal bile acid excretion, but increased fecal fatty acid excretion and respiratory exchange ratio when fed a high-fat/high-cholesterol diet | 27146480 |
| 2017-08-05 12:49:00 | Current studies suggest that increased Cyp7a1 expression and bile acid synthesis ameliorate hepatic inflammation through activation of FXR | 27534992 |
| Type | IDs |
|---|---|
| Synonymous | CYPVII, CYPVIIc |
| Gene |
UniProtKB-ID:
CP7A1_MOUSE
UniprotKB:
Q64505
UniParc:
UPI0000022E25
EMBL:
AL772306,
AK050020,
AK050260,
L23754,
AK050210,
AK050220
Ensembl:
ENSMUSG00000028240
KO:
mmu:13122
|
| Nucleutide sequences |
EMBL-CDS:
BAC34150.1,
BAC34131.1,
AAA68867.1,
BAC34033.1,
BAC34123.1
Ensembl_TRS:
ENSMUST00000029905
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000029905
RefSeq:
NP_031850.2
|
| Others |
UniRef100:
UniRef100_Q64505
UniRef90:
UniRef90_P18125
UniRef50:
UniRef50_P18125
UniGene:
Mm.57029
CCDS:
CCDS17950.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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