| Type | Description |
|---|---|
| Definition | cytochrome P450, family 51 |
| Date | Results | Publications |
|---|---|---|
| 2018-10-20 10:40:00 | we identify a global and sex-dependent transcriptional de-regulation due to the block in cholesterol synthesis during development of the Cyp51 knockout mice and provide in vivo evidence that sterol intermediates downstream of lanosterol may regulate the hepatic RORC activity. | 28098217 |
| 2017-12-16 10:19:00 | CYP51 is a mediator of T3 and FSH-induced follicular development. | 28938463 |
| 2015-11-28 10:38:00 | Our Cyp51 LKO model shows that steatosis appears with dietary fats in the absence of dietary cholesterol and its synthesis, while a block in the cholesterol pathway leads to NASH-like features | 25739789 |
| 2013-11-02 11:35:00 | germ cell-specific ablation of Cyp51, leading to lack of MAS, did not affect testicular morphology, daily sperm production, or reproductive performance in males. | 23509403 |
| 2011-10-22 10:24:00 | Cyp51 knock-out mice provide evidence that Cyp51 is essential for embryogenesis and present a potential animal model for studying ABS syndrome in humans. | 21705796 |
| Type | IDs |
|---|---|
| Synonymous | AI426508, CYPLI, Cyp51a1, Ldm, P450-14DM, P450LI |
| Gene |
UniProtKB-ID:
CP51A_MOUSE
UniprotKB:
Q8K0C4
UniParc:
UPI0000020B79
EMBL:
CH466600,
AK031059,
AF204804,
AF204798,
AF204801,
BC031813,
AF204803,
AF204796,
AK076983,
AF204802,
AF204797,
AF166266,
AF204800,
AK028355,
AF204799,
AK028815
Ensembl:
ENSMUSG00000001467
KO:
mmu:13121
|
| Nucleutide sequences |
EMBL-CDS:
BAC26134.1,
AAF74562.1,
AAF73986.1,
BAC27231.1,
BAC36548.1,
EDL14627.1,
AAH31813.1,
BAC25900.1
Ensembl_TRS:
ENSMUST00000001507
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000001507
RefSeq:
NP_064394.2
|
| Others |
UniRef100:
UniRef100_Q8K0C4
UniRef90:
UniRef90_Q8K0C4
UniRef50:
UniRef50_Q8K0C4
UniGene:
Mm.140158
CCDS:
CCDS19071.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员