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13119 Cyp4a14

13119

Cyp4a14

cytochrome P450, family 4, subfamily a, polypeptide 14

protein-coding

Mus musculus

基因描述

Type Description
Definition cytochrome P450, family 4, subfamily a, polypeptide 14

研究结论

Date Results Publications
2018-04-28 12:02:00 CYP4A14 may represent a useful target for the treatment of AngII-associated renal damage. 29277328
2018-04-28 11:56:00 this study provides a link between CYP4A14 and NAFLD. Overexpression of CYP4A14 promotes, whereas gene disruption of CYP4A14 attenuates, HFD- and MCD-induced liver lipid accumulation. Ablation of CYP4A14 gene markedly attenuates liver damage, inflammation, and fibrosis in MCD-induced NASH. 28270609
2017-12-02 10:59:00 Hypertension in Cyp4a14(-/-) male mice was accompanied by decreased renal perfusion and reduced glomerular filtration rates 28912346
2015-06-20 11:32:00 These results implicate Cyp4a10 and Cyp4a14 in the regulation of the host inflammatory response to enteropathogenic bacterial infection but not to acute aseptic inflammation. 24413902
2012-07-14 10:34:00 DEHP exposure did not influence lipase activity, whereas it slightly enhanced UGT activity and exclusively increased CYP4A14 levels in pregnant and/or postpartum dams. 22159897

名称对应

Type IDs
Synonymous AI314743
Gene
UniProtKB-ID: CP4AE_MOUSE
UniprotKB: O35728
UniParc: UPI0000022F96
EMBL: Y11640, AK149392, Y11641, Y11638, AK165452, BC089609, AL627182, Y11642, Y11639
Ensembl: ENSMUSG00000028715
KO: mmu:13119
Nucleutide sequences
EMBL-CDS: BAE38193.1, BAE28849.1, CAA72345.1
Ensembl_TRS: ENSMUST00000030487
Protein sequencees
Ensembl_PRO: ENSMUSP00000030487
RefSeq: XP_017175435.1, XP_006502787.2, NP_031848.1
Others
UniRef100: UniRef100_O35728
UniRef90: UniRef90_O35728
UniRef50: UniRef50_Q02928
UniGene: Mm.250901
CCDS: CCDS18491.1

全选

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研究热度

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