Cyp3a13 - cytochrome P450, family 3, subfamily a, polypeptide 13-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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13113 Cyp3a13

基因描述

Type	Description
Definition	cytochrome P450, family 3, subfamily a, polypeptide 13

研究结论

Date	Results	Publications
2018-09-15 10:19:00	A significant increase of Cyp3a13 transcript level and protein expression was found in the liver and hippocampi during spontaneous recurrent seizures in mice.	29125184
2014-03-08 12:33:00	CYP3A13 occurs naturally in aortic tissue.	23656416
2011-05-28 10:50:00	Oxygen acts primarily through the complex CYP3A13 (sensor)/endothelin-1 (effector) and, in an accessory way, directly onto endothelin-1. However, even without CYP3A13, the ductus arteriosus may close postnatally thanks to the contribution of ET-1.	21193583
2010-01-21 00:00:00	Genomic structure and regulation of CYP3a13.	12958193

名称对应

Type	IDs
Synonymous	IIIAm2
Gene	UniProtKB-ID: CP3AD_MOUSE, Q3UW87_MOUSE UniprotKB: Q64464, Q3UW87 UniParc: UPI00000232C0 EMBL: AK136529, AK149572, AK136494, AY823670, BC046592, X63023 Ensembl: ENSMUSG00000029727 KO: mmu:13113
Nucleutide sequences	EMBL-CDS: CAA44754.1, AAH46592.1, BAE23008.1, BAE28966.1, BAE23029.1, AAX39491.1 Ensembl_TRS: ENSMUST00000031741
Protein sequencees	Ensembl_PRO: ENSMUSP00000031741 RefSeq: XP_030109981.1, NP_031845.1
Others	UniRef100: UniRef100_Q64464 UniRef90: UniRef90_P51538 UniRef50: UniRef50_P08684 UniGene: Mm.289886 CCDS: CCDS19781.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
30910785	An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials. Drug Metab Dispos C J Henderson , Y Kapelyukh , N Scheer , A Rode , A W McLaren , A K MacLeod , D Lin , J Wright , L A Stanley , C R Wolf	2019-06-01	-
29125184	Hepatic and hippocampal cytochrome P450 enzyme overexpression during spontaneous recurrent seizures. Epilepsia Leonie Runtz , Benoit Girard , Marion Toussenot , Julie Espallergues , Alexis Fayd'Herbe De Maudave , Alexandre Milman , Frederic deBock , Chaitali Ghosh , Nathalie C GuÃ©rineau , Jean-Marc Pascussi , Federica Bertaso , Nicola Marchi	2018-01-01	-
27638959	Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans. J Lipid Res Shogo Takahashi , Tatsuki Fukami , Yusuke Masuo , Chad N Brocker , Cen Xie , Kristopher W Krausz , C Roland Wolf , Colin J Henderson , Frank J Gonzalez	2016-12-01	-
26903378	Thalidomide-induced limb abnormalities in a humanized CYP3A mouse model. Sci Rep Yasuhiro Kazuki , Masaharu Akita , Kaoru Kobayashi , Mitsuhiko Osaki , Daisuke Satoh , Ryo Ohta , Satoshi Abe , Shoko Takehara , Kanako Kazuki , Hiroshi Yamazaki , Tetsuya Kamataki , Mitsuo Oshimura	2016-01-01	-
23709690	Knockout of mouse Cyp3a gene enhances synthesis of cholesterol and bile acid in the liver. J Lipid Res Mari Hashimoto , Kaoru Kobayashi , Mio Watanabe , Yasuhiro Kazuki , Shoko Takehara , Asumi Inaba , Shin-Ichiro Nitta , Naoto Senda , Mitsuo Oshimura , Kan Chiba	2013-08-01	-
23656416	Mouse aortic muscle cells respond to oxygen following cytochrome P450 3A13 gene transfer. Can. J. Physiol. Pharmacol. Enrica Ciofini , Francesca Scebba , Stefano Luin , Daria Sodini , Debora Angeloni , Flavio Coceani	2013-05-01	Cyp3a13
23125282	Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans. Hum. Mol. Genet. Yasuhiro Kazuki , Kaoru Kobayashi , Sasitorn Aueviriyavit , Takeshi Oshima , Yoshimi Kuroiwa , Yasuko Tsukazaki , Naoto Senda , Hiroki Kawakami , Sumio Ohtsuki , Satoshi Abe , Masato Takiguchi , Hidetoshi Hoshiya , Naoyo Kajitani , Shoko Takehara , Kinya Kubo , Tetsuya Terasaki , Kan Chiba , Kazuma Tomizuka , Mitsuo Oshimura	2013-02-01	Cyp3a59, Cyp3a13, Cyp3a57
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21677750	A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley	2011-06-15	-
21193583	Cytochrome P-450 3A13 and endothelin jointly mediate ductus arteriosus constriction to oxygen in mice. Am J Physiol Heart Circ Physiol Barbara Baragatti , Enrica Ciofini , Francesca Scebba , Debora Angeloni , Daria Sodini , Stefano Luin , Gian Michele Ratto , Virginia Ottaviano , Eleonora Pagni , Aldo Paolicchi , Simona Nencioni , Flavio Coceani	2011-03-01	-

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