Cyp2c39 - cytochrome P450, family 2, subfamily c, polypeptide 39-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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13098 Cyp2c39

基因描述

Type	Description
Definition	cytochrome P450, family 2, subfamily c, polypeptide 39

研究结论

Date	Results	Publications
2010-01-21 00:00:00	By comparison of active site architectures between CYP2C38 and CYP2C39, the possible reasons affecting their substrate binding were proposed	19358898
2010-01-21 00:00:00	CYP2C39 is a novel retinoic acid 4-hydroxylase	14623888

名称对应

Type	IDs
Synonymous	CYPIIC39
Gene	UniProtKB-ID: CP239_MOUSE UniprotKB: P56656 UniParc: UPI0000192E02 EMBL: AC139233, AF047726, CH466534, AC117790, BC139290, BC139291 Ensembl: ENSMUSG00000025003 KO: mmu:13098
Nucleutide sequences	EMBL-CDS: AAI39291.1, AAD13721.1, AAI39292.1, EDL41819.1 Ensembl_TRS: ENSMUST00000025968
Protein sequencees	Ensembl_PRO: ENSMUSP00000025968 RefSeq: NP_034133.2, NP_001360866.1
Others	UniRef100: UniRef100_P56656 UniRef90: UniRef90_P56656 UniRef50: UniRef50_P10632 UniGene: Mm.42101 CCDS: CCDS29795.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
23260145	Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell Sylvia F Boj , Johan H van Es , Meritxell Huch , Vivian S W Li , Anabel JosÃ© , Pantelis Hatzis , Michal Mokry , Andrea Haegebarth , Maaike van den Born , Pierre Chambon , Peter Voshol , Yuval Dor , Edwin Cuppen , Cristina Fillat , Hans Clevers	2012-12-21	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21677750	A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley	2011-06-15	-
19358898	A comparative analysis of binding sites between mouse CYP2C38 and CYP2C39 based on homology modeling, molecular dynamics simulation and docking studies. Biochim. Biophys. Acta Xuan-Yu Meng , Qing-Chuan Zheng , Hong-Xing Zhang	2009-07-01	Cyp2c38, Cyp2c39
17435174	Altered vitamin A homeostasis and increased size and adiposity in the rdh1-null mouse. FASEB J. Min Zhang , Peirong Hu , Charles R Krois , Maureen A Kane , Joseph L Napoli	2007-09-01	Rdh1, Canx, Cyp26a1, Cyp2c39, Cyp26b1
18160786	Emergence of complex rearrangements at translocation breakpoints in a transgenic mouse; implications for mechanisms involved in the formation of chromosome rearrangements. Cytogenet. Genome Res. F Kasai , M Yoshihara , S Matsukuma , P O'Brien , M A Ferguson-Smith	2007-01-01	Cyp2c50, Cyp2c37, Cyp2c38, Cyp2c39, Cyp2c40, Cyp2c70, Cyp2c54, Cyp2c68, Cyp2c67, D19Mit19, Tmed11
16934000	Integrating genetic and network analysis to characterize genes related to mouse weight. PLoS Genet. Anatole Ghazalpour , Sudheer Doss , Bin Zhang , Susanna Wang , Christopher Plaisier , Ruth Castellanos , Alec Brozell , Eric E Schadt , Thomas A Drake , Aldons J Lusis , Steve Horvath	2006-08-18	-
14623888	Mouse liver CYP2C39 is a novel retinoic acid 4-hydroxylase. Its down-regulation offers a molecular basis for liver retinoid accumulation and fibrosis in aryl hydrocarbon receptor-null mice. J Biol Chem Fausto Andreola , Graham P Hayhurst , Gang Luo , Stephen S Ferguson , Frank J Gonzalez , Joyce A Goldstein , Luigi M De Luca	2004-01-30	-
12477932	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team	2002-12-24	-
9721182	Cloning and expression of murine CYP2Cs and their ability to metabolize arachidonic acid. Arch. Biochem. Biophys. G Luo , D C Zeldin , J A Blaisdell , E Hodgson , J A Goldstein	1998-09-01	Cyp2c29, Cyp2c37, Cyp2c38, Cyp2c39, Cyp2c40

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